Computational periscopy with an ordinary digital camera This work was made openly accessible by BU Faculty. Please share how this access benefits you. Your story matters.Computing the proportions of light arriving from different directions allows a diffusely reflecting surface to play the role of a mirror in a periscope. Such computational periscopy has previously depended on light travel distances being proportional to times of flight and thus has mostly been achieved with expensive, specialized ultrafast optical systems 1-12 . We introduce a 2D computational periscopy technique that requires only a single photograph captured with an ordinary digital camera. Our technique recovers the position of an opaque object and the scene behind (but not completely obscured by) the object, where both the object and scene are outside the line of sight of the camera, without requiring controlled or time-varying illumination. Non-line-of-sight imaging with only inexpensive, ubiquitous equipment may have considerable value in monitoring of hazardous environments, navigation, and detecting hidden adversaries.

Traditional paper-and-pencil neuropsychological batteries used to document cognitive deficits in multiple sclerosis (MS) patients lack timing precision. This makes it difficult to accurately measure psychomotor slowing, a central cognitive symptom of MS. Additionally, traditional batteries lack multiple alternate forms necessary to control for practice effects when assessing cognition over time. Finally such batteries are lengthy and expensive. Computerized neuropsychological batteries address many of these shortcomings. They measure response time more precisely, require less administration time, include alternate forms, and are ideal for rapid screening/triage. Although there are normative data on the reliability and validity of computerized measures, there have been no controlled validation studies with MS patients. The current study was designed to validate a computerized neuropsychological battery (ANAM) for use with relapsing-remitting (RR) MS patients. Prior to initiation of interferon-beta-1a (Avonex) treatment, subjects participated in a neuropsychological evaluation consisting of traditional and computerized measures. Moderate-to-high correlations were found between computerized and traditional measures. Computerized tests accurately predicted performance on key traditional tests. The battery was also concordant with traditional measures in identifying RR MS patients with and without neurocognitive impairment. Findings are discussed with respect to increased accuracy and accessibility of neuropsychological evaluations for MS patients.

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