Of the 206 patients who contracted Severe Acute Respiratory Syndrome (SARS) in Singapore five developed large artery cerebral infarctions. Four patients were critically-ill and three died. Intravenous immunoglobulin was given to three patients. An increased incidence of deep venous thrombosis and pulmonary embolism was also observed among the critically-ill patients. We believe our experience warrants an increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombotic tendency, is contemplated.

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Prepare-and-measure (P&M) quantum networks are the basic building blocks of quantum communication and cryptography. These networks crucially rely on non-orthogonal quantum encodings to distribute quantum correlations, thus enabling superior communication rates and informationtheoretic security. Here, we present a computational toolbox that is able to efficiently characterise the set of input-output probability distributions for any discrete-variable P&M quantum network, assuming only the inner-product information of the quantum encodings. Our toolbox is thus highly versatile and can be used to analyse a wide range of quantum network protocols, including those that employ infinite-dimensional quantum code states. To demonstrate the feasibility and efficacy of our toolbox, we use it to reveal new results in multipartite quantum distributed computing and quantum cryptography. Taken together, these findings suggest that our method may have implications for quantum network information theory and the development of new quantum technologies. arXiv:1803.04796v2 [quant-ph]

Device-independent quantum key distribution (DIQKD) is the art of using untrusted devices to distribute secret keys in an insecure network. It thus represents the ultimate form of cryptography, offering not only information-theoretic security against channel attacks, but also against attacks exploiting implementation loopholes. In recent years, much progress has been made towards realising the first DIQKD experiments, but current proposals are just out of reach of today’s loophole-free Bell experiments. Here, we significantly narrow the gap between the theory and practice of DIQKD with a simple variant of the original protocol based on the celebrated Clauser-Horne-Shimony-Holt (CHSH) Bell inequality. By using two randomly chosen key generating bases instead of one, we show that our protocol significantly improves over the original DIQKD protocol, enabling positive keys in the high noise regime for the first time. We also compute the finite-key security of the protocol for general attacks, showing that approximately 108–1010 measurement rounds are needed to achieve positive rates using state-of-the-art experimental parameters. Our proposed DIQKD protocol thus represents a highly promising path towards the first realisation of DIQKD in practice.

Measurement-device-independent quantum key distribution (MDI-QKD) is the only known QKD scheme that can completely overcome the problem of detection side-channel attacks. Yet, despite its practical importance, there is no standard approach towards proving the security of MDI-QKD. Here, we present a simple numerical method that can efficiently compute almost-tight security bounds for any discretely modulated MDI-QKD protocol. To demonstrate the broad utility of our method, we use it to analyze the security of coherent-state MDI-QKD, decoy-state MDI-QKD with leaky sources, and a variant of twin-field QKD called phase-matching QKD. In all of the numerical simulations (using realistic detection models) we find that our method gives significantly higher secret key rates than those obtained with current security proof techniques. Interestingly, we also find that phase-matching QKD using only two coherent test states is enough to overcome the fundamental rate-distance limit of QKD. Taken together, these findings suggest that our security proof method enables a versatile, fast, and possibly optimal approach towards the security validation of practical MDI-QKD systems.

Device-independent quantum key distribution (DIQKD) offers the prospect of distributing secret keys with only minimal security assumptions, by making use of a Bell violation. However, existing DIQKD security proofs have low noise tolerances, making a proof-of-principle demonstration currently infeasible. We investigate whether the noise tolerance can be improved by using advantage distillation, which refers to using two-way communication instead of the one-way error-correction currently used in DIQKD security proofs. We derive an efficiently verifiable condition to certify that advantage distillation is secure against collective attacks in a variety of DIQKD scenarios, and use this to show that it can indeed allow higher noise tolerances, which could help to pave the way towards an experimental implementation of DIQKD.

This paper aims to identify the current challenges facing the sustainable development of island tourism and to develop a new conceptual approach to sustainable development based upon optimisation. The optimisation process for island tourism will be discussed through the development of a new life cycle model -the multifunctional interactive process cycle that is calibrated using a set of 15 island tourism status indicators. The paper also seeks to explain how a complex and dynamic tourism system can be developed that takes a destination towards an optimal sustainable state to satisfy both visitors and the local community. Copyright

The authors describe diffusion-weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) changes in the hippocampus within 48 hours of acute symptomatic seizures or status epilepticus in 12 patients. DWI showed increased signal and a decreased apparent diffusion coefficient (ADC) in all patients, with corresponding lactate detected on MRS in six patients and EEG seizure activity in nine patients. On follow-up, the atrophic hippocampus had an increased ADC in six patients. DWI and MRS may predict development of hippocampal sclerosis.