These data support the efficacy of prazosin for nightmares, sleep disturbance, and other PTSD symptoms.

Background-Prazosin, a CNS active alpha-1 adrenoreceptor antagonist, has reduced nightmares and sleep disturbance in placebo controlled studies of combat-related PTSD. We evaluated objective sleep parameters and PTSD symptoms in a placebo-controlled prazosin trial for civilian traumarelated PTSD.

No abstract

Smoking-cessation interventions can be safely incorporated into routine mental health care for PTSD and are more effective than treatment delivered separately by a specialized smoking-cessation clinic. Integrating cessation treatment into psychiatric care may have the potential for improving smoking quit rates in other populations of chronically mentally ill smokers.