Hyperventilation evoked abnormal EEG discharges or discharges and clinical seizures in 11% our patients with partial complex seizures. Hyperventilation is useful in the diagnosis of this kind of epilepsy, but may need to be pursed more vigorously and for a longer duration than is usual practice. The vigorous use of hyperventilation in selected patients with partial seizures should be employed before the use of other more complicated, expensive, and potentially harmful activating procedures.
Neuronal ceroid-lipofuscinosis is manifested by visual and intellectual deterioration and seizures. Autofluorescent lipopigments are found in neural and many nonneural tissues, with characteristic staining and ultrastructural properties. Presumptive diagnosis can usually be made on the basis of history, physical examination, and electrodiagnostic tests, but in the absence of a specific biochemical defect, histologic confirmation is essential. A 6-year-old boy with the clinical appearance of the juvenile form of the disease had sea-blue histiocytes in the bone marrow, and curvilinear profiles in ultrastructural inclusions in skin biopsy tissue, cultured skin fibroblasts, and bone marrow cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.