HighlightsNeonatal handling affects the developmental course of cannabinoid receptors in rat brain.In adult handled rats, [3H]CP55,940 binding levels are reduced in CPu, NAc and BLA.Dorsal hippocampal [3H]CP55,940 binding levels are reduced only in female handled rats.Handling increases adolescent and decreases adult [3H]CP55,940 binding levels in mPFC.
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