In this study, we report a novel and efficient synthetic
method
to construct isoquinolone scaffold via the Rh(III)-catalyzed
(4 + 2) annulation of benzamide with an unreported coupling reagent
methyl 2-chloroacrylate. Accordingly, other valuable 1,2-benzothiazine
and naphtho[1′,2′:4,5]imidazo[1,2-a]pyridine derivatives are also obtained through a similar synthetic
protocol. Thus, our developed method is highlighted by high yield
and reaction versatility.
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