Interethnic prejudice in children has been studied mostly in the United States, but less often in Europe, where the public discourse is increasingly negative about ethnic minorities, especially the Muslim minority. This study examined in-group favoritism (White preference) and out-group rejection of children of Middle Eastern descent (representing the Muslim minority) among White children in the Netherlands. Social preference for and rejection of children of Middle Eastern descent are compared with preference for and rejection of Black children. Social preference and rejection were measured using a task in which participants were presented with pictures of children with different ethnic appearances, and asked to select who they wanted to (not) play with, (not) sit next to, and invite for their birthday party. In addition, maternal implicit prejudice against people of Middle Eastern descent and explicit attitudes toward their children’s interethnic contact were assessed. The study included 140 children aged 6 to 8 years ( M = 7.26, SD = 0.77) and their mothers. The results reveal both in-group favoritism and out-group rejection. The Middle Eastern out-group was preferred less than the Black out-group. Reporting absolutely no reservations about children’s interethnic contact by mothers was associated with less rejection of children of Middle Eastern descent. Findings reveal that young children already show interethnic prejudice and that particularly people of Middle Eastern descent are devalued. The results show that maternal acceptance of child interethnic contact seems to play a role, and provide starting points for further investigation of the relation between parental and child interethnic attitudes.