Purpose
This study aimed to explore the clinical value of ultrasonic Doppler examination and contrast‐enhanced ultrasound (US) in the circulation of septic acute kidney injury (AKI).
Methods
Patients with intensive care unit‐related infection were divided into AKI group and control groups. The AKI group was divided into three subgroups according to the serum creatinine value: stage 1, stage 2, and stage 3. Relevant parameters and blood flow of the renal artery were measured, and further contrast‐enhanced US was performed and time‐intensity curve was analyzed.
Results
The renal blood flow (RBF) and time‐averaged velocity decreased significantly in the AKI group compared with the control group (p = .021 and p = .001). The peak value decreased and time to peak (TTP) prolonged in the AKI group (p < .001). With the aggravation of the disease, the RBF decreased slightly among subgroups (p = 0.124). However, the peak value gradually decreased and the TTP prolonged (all p < .05). The multiple linear regression model showed that only PI, RI, and TTP were independently and linearly correlated with the serum creatinine value.
Conclusions
Doppler US and contrast‐enhanced US are of great help in the detection of condition changes and prognosis of patients with sepsis‐induced AKI.
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