The measurement scales, consistency index, inconsistency issues, missing judgment estimation and priority derivation methods have been extensively studied in the pairwise comparison matrix (PCM). Various approaches have been proposed to handle these problems, and made great contributions to the decision making. This paper reviews the literature of the main developments of the PCM. There are plenty of literature related to these issues, thus we mainly focus on the literature published in 37 peer reviewed international journals from 2010 to 2015 (searched via ISI Web of science). We attempt to analyze and classify these literatures so as to find the current hot research topics and research techniques in the PCM, and point out the future directions on the PCM. It is hoped that this paper will provide a comprehensive literature review on PCM, and act as informative summary of the main developments of the PCM for the researchers for their future research.
Three blue‐light emitting dipyrenylbenzene derivatives, 1‐(4‐(1‐pyrenyl)phenyl)pyrene (PPP), 1‐(2,5‐dimethoxy‐4‐(1‐pyrenyl)phenyl)pyrene (DOPPP), and 1‐(2,5‐dimethyl‐4‐(1‐pyrenyl)phenyl)pyrene (DMPPP), have been prepared by the Suzuki coupling reaction of aryl dibromides with pyreneboronic acid in high yields. These compounds exhibit high glass‐transition temperatures of 97–137 °C and good film‐forming ability. As revealed from single‐crystal X‐ray analysis, these dipyrenylbenzenes adopt a twisted conformation with inter‐ring torsion angles of 44.5°–63.2° in the solid state. The twisted structure is responsible for the low degree of aggregation in the thin films that leads to fluorescence emission of the neat films at 446–463 nm, which is shorter than that of the typical pyrene excimer emission. The low degree of aggregation is also conducive for the observed high fluorescence quantum yields of 63–75%. In organic light‐emitting diode (OLED) applications, these dipyrenylbenzenes can be used as either the charge transporter or host emitter. The non‐doped blue OLEDs that employ these compounds as the emissive layer can achieve a very high external quantum efficiency (ηext) of 4.3–5.2%. In particular, the most efficient DMPPP‐based device can reach a maximum ηext of 5.2% and a very high luminescence of 40 400 cd m–2 in the deep‐blue region with Commission Internationale d'Énclairage (CIE) coordinates of (0.15, 0.11).
a b s t r a c tThe derivation of a priority vector from a pair-wise comparison matrix (PCM) is an important issue in the Analytic Hierarchy Process (AHP). The existing methods for the priority vector derivation from PCM include eigenvector method (EV), weighted least squares method (WLS), additive normalization method (AN), logarithmic least squares method (LLS), etc. The derived priority vector should be as similar to each column vector of the PCM as possible if a pair-wise comparison matrix (PCM) is not perfectly consistent. Therefore, a cosine maximization method (CM) based on similarity measure is proposed, which maximizes the sum of the cosine of the angle between the priority vector and each column vector of a PCM. An optimization model for the CM is proposed to derive the reliable priority vector. Using three numerical examples, the CM is compared with the other prioritization methods based on two performance evaluation criteria: Euclidean distance and minimum violation. The results show that the CM is flexible and efficient.
The network of stemness genes and oncogenes in human patient-specific reprogrammed cancer stem cells (CSCs) remains elusive, especially in liver cancer. HepG2-derived induced pluripotent stem cell-like cells (HepG2-iPS-like cells) were generated by introducing Yamanaka factors and the knockdown vector shTP53. They exhibited features of stemness and a higher tumorigenesis after xenograft transplantation compared with HepG2 cells. The cancerous mass of severe combined immunodeficiency (SCID) mice derived from one colony was dissected and cultured to establish reprogrammed HepG2-derived CSC-like cells (designated rG2-DC-1C). A single colony exhibited 42% occurrence of tumors with higher proliferation capacities. rG2-DC-1C showed continuous expression of the OCT4 stemness gene and of representative tumor markers, potentiated chemoresistance characteristics, and invasion activities. The sphere-colony formation ability and the invasion activity of rG2-DC-1C were also higher than those of HepG2 cells. Moreover,
An experimental study with MPIV (micro particle image velocimetry) flow visualization of incompressible liquid flow in a microchannel is presented. Deionized water served as a working medium. The channel was microfabricated in a PMMA substrate using an excimer laser, and was 115 µm deep, 200 µm wide and 24 000 µm long with a hydraulic diameter of about 146 µm. The pressure drop between the inlet and the outlet of the duct as well as mass flow rates were measured and friction factors were calculated for different Reynolds numbers. Data were discussed and compared with those of previous investigations of similar studies. Moreover, time evolutions of the microflow at the middle of the microchannel at Re = 50, 100, 470 and 900 were photographed. Hydrodynamic entry length correlations were found for both laminar and turbulent flow in the present microchannel.
Eukaryotic organisms require oxygen homeostasis to maintain proper cellular function for survival. During conditions of low oxygen tension (hypoxia), cells activate the transcription of genes that induce an adaptive response, which supplies oxygen to tissues. Hypoxia and hypoxia-inducible factors (HIFs) may contribute to the maintenance of putative cancer stem cells, which can continue self-renewal indefinitely and express stemness genes in hypoxic stress environments (stem cell niches). Reactive oxygen species (ROS) have long been recognized as toxic by-products of aerobic metabolism that are harmful to living cells, leading to DNA damage, senescence, or cell death. HIFs may promote a cancer stem cell state, whereas the loss of HIFs induces the production of cellular ROS and activation of proteins p53 and p16(Ink4a), which lead to tumor cell death and senescence. ROS seem to inhibit HIF regulation in cancer cells. By contrast, controversial data have suggested that hypoxia increases the generation of ROS, which prevents hydroxylation of HIF proteins by inducing their transcription as negative feedback. Moreover, hypoxic conditions enhance the generation of induced pluripotent stem cells (iPSCs). During reprogramming of somatic cells into a PSC state, cells attain a metabolic state typically observed in embryonic stem cells (ESCs). ESCs and iPSCs share similar bioenergetic metabolisms, including decreased mitochondrial number and activity, and induced anaerobic glycolysis. This review discusses the current knowledge regarding the emerging roles of ROS homeostasis in cellular reprogramming and the implications of hypoxic regulation in cancer development.
A series of gold precursor solutions are prepared by dissolving HAuCl4 and its mixtures with K2CO3 of different contents in deionized (DI) water. Neat HAuCl4 predominately forms AuCl4 – ions in an aqueous solution. In the presence of K2CO3, AuCl4 – ions hydrolyze to form [AuCl4–x (OH) x ]− complex ions. Increasing the content of K2CO3 in a gold precursor solution increases the content of [AuCl4–x (OH) x ]− complex ions and decreases the content of AuCl4 – ions. Poly(4-vinyl pyridine) (P4VP) films of two different molecular weights are deposited on SiO x /Si by spin coating, by which the thicknesses are controlled by polymer weight fractions in butanol. Those P4VP films form periodic wrinkles when immersed in aqueous solutions, followed by drying. The surface wrinkling is induced by swelling pressure that overwhelms the mechanical property of the P4VP film. The periodicity and amplitude of wrinkles grown on the P4VP films strongly correlate with initial thickness, AuCl4 – ion content, and residual stress.
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