Background: Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan and has quickly spread across the world. The mortality rate in critically ill patients with COVID-19 is high. This study analyzed clinical and biochemical parameters between mild and severe patients, helping to identify severe or critical patients early. Methods: In this single center, cross-sectional study, 143 patients were included and divided to mild/moderate and sever/critical groups. Correlation between the disease criticality and clinical features and peripheral blood biochemical markers was analyzed. Cutoff values for critically ill patients were speculated through the ROC curve.

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Objectives: To evaluate the prevalence of cardiac injury and its association with mortality in hospitalized patients infected with avian influenza A (H7N9) virus. Design: Retrospective cohort study. Setting: A total of 133 hospitals in 17 provinces, autonomous regions, and municipalities of mainland China that admitted influenza A (H7N9) virus–infected patients between January 22, 2015, and June 16, 2017. Patients: A total of 321 patients with influenza A (H7N9) virus infection were included in the final analysis. Interventions: None. Measurements and Main Results: Demographics and clinical characteristics were collected from medical records. Cardiac injury was defined according to cardiac biomarkers, electrocardiography, or echocardiography. Among the 321 patients, 203 (63.2%) showed evidence of cardiac injury. Compared with the uninjured group, the cardiac injury group had lower Pao 2/Fio 2 (median, 102.0 vs 148.4 mm Hg; p < 0.001), higher Acute Physiology and Chronic Health Evaluation II score (median, 17.0 vs 11.0; p < 0.001), longer stay in the ICU (10.0 vs 9.0 d; p = 0.029), and higher proportion of in-hospital death (64.0% vs 20.3%; p < 0.001). The proportion of virus clearance until discharge or death was lower in the cardiac injury group than in the uninjured group (58.6% vs 86.4%; p < 0.001). Multivariable-adjusted Cox proportional hazards regression analysis showed that cardiac injury was associated with higher mortality (hazards ratio, 2.06; 95% CI, 1.31–3.24) during hospitalization. Conclusions: Cardiac injury is a frequent condition among hospitalized patients infected with influenza A (H7N9) virus, and it is associated with higher risk of mortality.

COVID-19 should not be the world's last public health disaster, so there is an urgent need to learn from COVID-19 to prepare better for the next public health disaster. This study aims to understand the factors that make people wear a face mask at the beginning of an outbreak of public health disaster. Semi-structured interviews were conducted during April 2020 in China, one month after the COVID-19 was declared a pandemic. The respondents were members of the public living in China, covering two age groups: young adults and older adults. They were recruited using a convenient sample and snowball sampling strategy. The results were analysed using content analysis. Seventeen subjects were recruited, among which nine were young adults (average age = 26.4; SD = 10.5), and eight were older adults (average age = 60.4; SD = 12.1). This study found that environmental factors, personal factors, factors concerning wearing masks, specific circumstances, and development of the pandemic were the common factors considered by both young adults and older adults. This study should help the authority formulate prevention policies better to reduce the risk of an outbreak if there is a new virus outbreak in the future, unfortunately.