This study investigated the incorporation of the plant growth promoter Vitazyme as an additional seed‐dressing component to pearl millet, along with a regularly recommended systemic fungicide. Preliminary in vitro examination indicated a significant enhancement in seedling vigor for all of the concentrations tested. Vitazyme seed treatments, alone or in combination with Apron 35SD, resulted in improved field emergence. Yield analyses indicated Vitazyme seed treatment alone or in combination with foliar spray showed yield measurements comparable to Apron 35SD. Furthermore, the combination of seed treatments/foliar applications with Apron 35SD provided the best yield improvement.