Bajakah Tampala merupakan tanaman asli Kalimantan Timur yang mempunyai aktivitas antibakteri, tetapi hingga saat ini aktivitas antibakteri dan antijamurnya terhadap S. aureus dan C. albicans belum ada yang melaporkan. Penelitian ini bertujuan untuk mengetahui potensi bajakah tampala sebagai antibakteri terhadap S. aureus dan antijamur C. albicans. Efektivitas antibakteri bajakah tampala terhadap S. aureus dan antijamur C. albicans dilakukan menggunakan metode microbroth dilution dengan melihat nilai minimal inhibitory concentration (MIC50). Ekstrak etanol kulit bajakah tampala mempunyai senyawa flavonoid, alkaloid dan terpenoid. Ekstrak etanol bajakah tampala mempunyai aktivitas terhadap antibakteri S. aureus serta antijamur C. albicans. Oleh karena itu, etanol kulit bajakah tampala dapat dikembangkan menjadi kandidat agen antibakteri dan atijamur terhadap S. aureus dan C. albicans.
Chronic inflammation is common in infectious diseases, rheumatoid arthritis, gout, and autoimmune diseases. However, using non-steroidal anti-inflammatory drugs (NSAIDs) is accompanied by dangerous side effects. Therefore, searching for safer alternative therapies without side effects is very important. A natural blend of ingredients produced by stingless bees from plants was potential as a remedy. Meanwhile, the potential of kelulut bee products from East Kalimantan as an anti-inflammatory is still unknown. This study aimed to compare the chemical composition of kelulut bee (Trigona apicalis) products and evaluate the anti-inflammatory effect of honey, propolis, and their combination. Propolis extract and honey were determined as secondary metabolites. An anti-inflammatory in vivo assay triggered the edema using carrageenan on male mice and measured its anti-inflammatory power value. Propolis extract and honey from T. apicalis have a promising anti-inflammatory effect and are significantly higher than the positive control. Meanwhile, combining propolis extract and honey did not enhance the anti-inflammatory effect. In addition, combining honey and propolis preparations with a ratio of 75 : 25 has a better effect on reducing edema volume than the other two combinations. Still, it is not better than the treatment with propolis extract or honey alone. The content of polyphenol compounds found in honey and propolis preparations is thought to have an important role in reducing edema volume.
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