Abstract. [Purpose] This study was done to determine the effect of a complex exercise on quadriceps activity and pain of elderly patients with knee osteoarthritis (OA) in a clinical setting.[Subjects] Ttwelve subjects over the age of 65, who were diagnosed with knee OA and hospitalized at a rehabilitation facility in the Republic of Korea, participated in this study.[Methods] All participants were supervised by an expert. They performed a program which consisted of stretch and strength exercises with traditional therapy for 10 weeks. The main outcome measures were assessed a pain scale and EMG data (%MVIC) of the rectus femoris (RF), vastus lateralis (VL), and vastus medialis (VM) at baseline, after 5 weeks of exercise, and after 10 weeks of exercise.[Results] There was no significant difference between the male and female groups in pain or quadriceps activity. After the 10-week intervention, all participants showed improvement of RF, VL and VM activities and had decreased knee pain.[Conclusions] Older patients with OA showed a reduction in knee pain and improvement quadriceps activity after performing a complex exercise program that might help to stabilize the knee.
The profile of membrane currents was investigated in differentiated neuronal cells derived from human neural stem cells (hNSCs) that were obtained from aborted fetal cortex. W hole-cell voltage clamp recording revealed at least 4 different currents: a tetrodotoxin (TTX)-sensitive Na + current, a hyperpolarization-activated inward current, and A-type and delayed rectifier-type K + outward currents. Both types of K + outward currents were blocked by either 5 mM tetraethylammonium (TEA) or 5 mM 4-aminopyridine (4-AP). The hyperpolarization-activated current resembled the classical K + inward current in that it exhibited a voltage-dependent block in the presence of external Ba 2+ (30μ M) or Cs + (3μ M). However, the reversal potentials did not match well with the predicted K + equilibrium potentials, suggesting that it was not a classical K + inward rectifier current. The other Na + inward current resembled the classical Na + current observed in pharmacological studies. The expression of these channels may contribute to generation and repolarization of action potential and might be regarded as functional markers for hNSCs-derived neurons.
[Purpose] The aim of this study was to investigate the EMG amplitude of the gluteus maximus (GMax) and medius (GMed) during 6 exercises with and without a pelvic belt.[Subjects] Twenty healthy males were recruited.[Methods] The belt was positioned below the anterior superior iliac spine. Surface EMG was used to measure the GMax and GMed activity of the dominant limb during exercise. The percentage of the EMG amplitude relative to maximal voluntary isometric contraction was analyzed with a mixed within-between subjects analysis of variance (ANOVA).[Results] This study showed significantly increased GMax activity in the pelvic belt condition as a main effect. However, there was no significant effect on GMed activity except with the hip clam.[Conclusion] The pelvic belt significantly improved GMax activity during exercises in contrast to the GMed activity. When treating people with weakness of gluteal muscles, the functional specific exercises with a pelvic belt have the beneficial effect of associated muscle strengthening.
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