SUMMARY The evolution of subjective sleep and sleep electroencephalogram (EEG) after hemispheric stroke have been rarely studied and the relationship of sleep variables to stroke outcome is essentially unknown. We studied 27 patients with first hemispheric ischaemic stroke and no sleep apnoea in the acute (1–8 days), subacute (9–35 days), and chronic phase (5–24 months) after stroke. Clinical assessment included estimated sleep time per 24 h (EST) and Epworth sleepiness score (ESS) before stroke, as well as EST, ESS and clinical outcome after stroke. Sleep EEG data from stroke patients were compared with data from 11 hospitalized controls and published norms. Changes in EST (>2 h, 38% of patients) and ESS (>3 points, 26%) were frequent but correlated poorly with sleep EEG changes. In the chronic phase no significant differences in sleep EEG between controls and patients were found. High sleep efficiency and low wakefulness after sleep onset in the acute phase were associated with a good long‐term outcome. These two sleep EEG variables improved significantly from the acute to the subacute and chronic phase. In conclusion, hemispheric strokes can cause insomnia, hypersomnia or changes in sleep needs but only rarely persisting sleep EEG abnormalities. High sleep EEG continuity in the acute phase of stroke heralds a good clinical outcome.

Background: Reports on the effects of focal hemispheric damage on sleep EEG are rare and contradictory. Patients and Methods: Twenty patients (mean age ± SD 53 ± 14 years) with a first acute hemispheric stroke and no sleep apnea were studied. Stroke severity [National Institute of Health Stroke Scale (NIHSS)], volume (diffusion-weighted brain MRI), and short-term outcome (Rankin score) were assessed. Within the first 8 days after stroke onset, 1–3 sleep EEG recordings per patient were performed. Sleep scoring and spectral analysis were based on the central derivation of the healthy hemisphere. Data were compared with those of 10 age-matched and gender-matched hospitalized controls with no brain damage and no sleep apnea. Results: Stroke patients had higher amounts of wakefulness after sleep onset (112 ± 53 min vs. 60 ± 38 min, p < 0.05) and a lower sleep efficiency (76 ± 10% vs. 86 ± 8%, p < 0.05) than controls. Time spent in slow-wave sleep (SWS) and rapid eye movement (REM) sleep and total sleep time were lower in stroke patients, but differences were not significant. A positive correlation was found between the amount of SWS and stroke volume (r = 0.79). The slow-wave activity (SWA) ratio NREM sleep/wakefulness was lower in patients than in controls (p < 0.05), and correlated with NIHSS (r = –0.47). Conclusion: Acute hemispheric stroke is accompanied by alterations of sleep EEG over the healthy hemisphere that correlate with stroke volume and outcome. The increased SWA during wakefulness and SWS over the healthy hemisphere contralaterally to large strokes may reflect neuronal hypometabolism induced transhemispherically (diaschisis).

Over the period between 06/00 and 03/03, 41 patients with different injuries of the upper cervical spine were treated by a halo fixator and were statistically recorded. The collective showed different injury patterns, 2 fractures of occiput condyles (5%), 3 Jefferson fractures (7%), 1 combined injury of the odontoid process and an atlas fracture (2%), 32 odontoid fractures (78%), 2 hanged-man-fractures Typ Effendi II (5%) and one case of pathologic fractures from the 2. to the 4. cervical vertebral body based on a plasmocytoma (2%). 31 of 41 patients could be examined for a follow up; 40 complete medical histories were well documented and could be analysed. As complications we had screw loosening in 6 cases (15%), a complete tear out of screws in 2 cases (5%). One patient took the halo away by himself two times, so after the second time surgical stabilisation was performed (2,5%). One case of intracranial penetration of a screw happened after the patient fell down in an accident with the halo (2,5%). Infection of the screw pins appeared in 4 cases (10%) and we had 2 cases of skin necrosis (5%). A second reduction after redisplacement was necessary in 8 cases (20%). 23 patients suffered from pain at the insertion of the screws (75%) and 18 patients complained of pressure in the head (58%). On the question of the comfort of this kind of therapy answered 18 patients with "intolerable" (58%), 10 patients with middle (32%) and 3 patients with tolerable (10%). Despite of the large number of different complications and the miscomfort of a halo fixator we think that there are still indications for treatment of special injuries of the upper cervical spine with a halo fixator. One important aspect is the lack of adequate alternatives even with regard to the biomechanical stability.

Carpal tunnel syndrome (CTS) was observed in 4 cases of a consecutive series of 16 patients admitted for the initial diagnosis or follow-up of systemic scleroderma from 1986 to 1990. We also observed one case of ulnar nerve compression. Neurological involvement was confirmed by electromyogram, and motor and sensory nerve conduction studies. The neurological signs appeared at the beginning of the disease in two cases and preceded the discovery of scleroderma in two. CTS is not rare in scleroderma and must be carefully sought, both clinically and electrophysiologically. Patients with ‘idiopathic’ CTS might need clinical follow-up for early diagnosis of scleroderma.

Zusammenfassung Gegenstand und Ziel: Dieser Beitrag soll über geschichtliche und heutige Behandlungsmethoden und Komplikationen beim Nabelbruch des Pferdes aufklären und dem Leser die rechtlichen Folgen von tierschutzwidrigem Handeln anhand eines Fallberichts aufzeigen. Ergebnisse: Bei einer Kleinpferd-Jährlingsstute wurde als Ursache wochenlang bestehender Schmerzen die Versorgung eines im Durchmesser 8,5–9,5 cm großen Nabelbruchs mit einem Gummiring und einer Strohband-Ligatur festgestellt. Nach Resektion der Umfangsvermehrung in Allgemeinanästhesie zeigte das Pferd ein ungestörtes Allgemeinbefinden. Die pathologisch-anatomische und histologische Untersuchung des Resektats wies erhebliche entzündliche Veränderungen des Gewebes nach, die als Ursache der länger anhaltenden Schmerzen angesehen werden müssen. Schlussfolgerung und klinische Relevanz: Die Behandlung eines Nabelbruchs durch Applikation von elastischen Ringen oder Ligaturen entspricht nicht der tierärztlichen Ethik. Sie ist darüber hinaus tierschutzwidrig und kann je nach Schweregrad als Ordnungswidrigkeit oder Straftatbestand geahndet werden.