Objective: The aim of this study is to analyze various rehabilitation protocol and determine which methods will yield a better outcome. Methods: The database reports were searched within 1990 until 2020, using PubMed, Cochrane library database, Ovid, Medline, and the other several published trials. A statistical analysis was made from Review Manager and Trial Sequential Analysis (TSA). Result: The mean of rerupture rate is 3.3% (n = 8) in the combination protocol and 8% (n = 48) in controlled active motion (CAM) protocol. Meta-analysis found no significant difference between Kleinert versus CAM in rerupture rate. Furhtermore, we found no significant difference in Duran versus CAM in rerupture rate. In TSA, the Z-curve does not cross both of the trial sequential boundaries, a further trial with larger sample will be required. The TSA of flexion contracture CAM versus Kleinert was indicated that CAM protocol may be superior than Kleinert to reduce the incidence of flexion contracture with the range of mean flexion contracture 6.6% (n = 18) in CAM to 23.6% (n = 76) in Kleinert protocol. Conclusion: Current meta-analysis proposed that the combination technique will result less rerupture incidence and better functional outcome in flexor zone II injuries than other techniques. The CAM method also results in less flexion contracture than others. However, a further meta-analysis with larger sample trials seems to be required to confirm this review's conclusion.
BACKGROUND: Anterior translation of the tibia (ATT) is a secondary sign of an anterior cruciate ligament (ACL) tear. With advances in technology, new tools such as the Lachmeter are expected to replace computed tomography scanning (CT scan) in measuring the ATT. AIM: This study aims to determine the diagnostic validity of the Lachmeter in measuring the ATT 6–12 months after ACL tear reconstruction. MATERIALS AND METHODS: A retrospective diagnostic test with a Lachmeter was used to measure ATT in patients 6–12 months after ACL tear reconstruction, compared with the gold standard CT scan and using a consecutive sampling technique. The optimal cutoff value of ATT was determined with Lachmeter afterwards. Statistical Package for the Social Sciences version 21.0 was used for the data analysis. RESULTS: There are 28 persons with a positive ATT (≥ 5 mm) and four people with a negative ATT (<5 mm) measured using CT scan out of 32 samples. The optimal cutoff of ATT with Lachmeter is ≥7.28 mm (Area under curve = 0.88, 95% CI, 0.67–1.00 and p = 0.004) with a sensitivity of 84.62%, specificity 83.33%, positive predictive value 95.65%, negative predictive value 55.56%, positive likelihood ratio (LR) 5.08, negative LR 0.18, and 84.38% accuracy. CONCLUSION: Lachmeter is a new tool for determining ATT that is highly efficient and easy to use. With good sensitivity and specificity values, this new tool has been proven to be very good at measuring ATT compared to CT scan as the gold standard.
Resumo Objetivo: O objetivo desta metanálise é comparar a cicatrização de ligamentos no autoenxerto e aloenxerto na reconstrução do ligamento cruzado anterior (LCA). Métodos: A seleção dos estudos adequados foi realizada de acordo com as diretrizes de Relatórios Preferenciais para Revisões Sistemáticas e Metanálises (Preferred Reporting Items for Systematic Reviews and Meta-Analyses – PRISMA). Uma análise estatística foi feita usando um gerente de revisão. Os relatórios eletrônicos foram pesquisados usando os bancos de dados PubMed, Medline e Cochrane Library. Os critérios de inclusão foram estudos em animais e a histologia celular de ambos os enxertos como desfecho. Resultado: A pesquisa inicial revelou 412 artigos potenciais. Após a retirada das duplicatas, restaram 246 artigos. Então, 14 artigos foram obtidos e selecionados pela relevância e elegibilidade. Os artigos relevantes foram pesquisados manualmente, verificando sua elegibilidade e detalhando os estudos para não perder os relatórios incluídos. Posteriormente, foram incluídos 5 estudos, com um total de 232 amostras, relatando os resultados de biópsia com histologia quantitativa de cicatrização de ligamento entre aloenxerto e autoenxerto. As amostras de biópsia nesses estudos foram examinadas sob microscópio leve ou eletrônico, para análise da área de distribuição celular e estágios de ligamentização em cada grupo. As metanálises encontraram diferença significativa entre autoenxerto e aloenxerto (Heterogeneidade, I2 = 89%; Diferença média, 95% intervalo de confiança [IC] = −34,92, −54,90, −14,93; p = 0,0006). Também há uma diferença significativa nos dois enxertos na contagem celular de mais de 24 semanas (Heterogeneidade, I2 = 26%; Diferença média, 95% IC = −14,59 , −16,24, −12,94; p < 0,00001). Conclusão: Na presente metanálise, o autoenxerto mostra resultados significativos quando comparado ao aloenxerto, com mais acúmulo celular e resposta de remodelagem mais rápida no processo de ligamentização sendo observado no primeiro. No entanto, será necessário um estudo clínico maior para enfatizar o resultado desta literatura.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.