Objectives. We sought to determine whether social class modifies the effect of BMI on breast cancer incidence. Methods. Participants included 5642 postmenopausal White women recruited in 1989 to CLUE II, a prospective cohort study in Washington County, Maryland. We obtained exposure data from CLUE II and the 1990 US Census. We used survival and random-effects Cox proportional hazards analyses to determine the association of social class and BMI with breast cancer incidence. Results. Education was independently associated with increased risk of breast cancer incidence (hazard ratio [HR] = 1.06; 95% confidence interval [CI] = 1.01, 1.11; P < .05); contextual measures of social class were not. Education modified the effect of BMI at age 21 years (HR = 0.98; 95% CI = 0.97, 0.99); area-level social class modified the effect of BMI at baseline (HR = 0.97; 95% CI = 0.94, 0.99) and BMI change (HR = 0.98; 95% CI = 0.95, 1.00). Subpopulation analyses that were adjusted for hormone use, parity, and breast-feeding found similar effects. Conclusions. Social class moderates the influence of body size on breast cancer incidence. Public health efforts, therefore, should advocate for policies that improve social conditions to decrease the burden of breast cancer.
Although the numbers of African-American women who are 'ever' screened for breast cancer has increased, sustaining regular screening over a lifetime remains a problem. Face-to-face interviews about breast cancer screening were conducted with 576 African-American women from an east coast city. The well-screened index measuring adherence to breast cancer screening guidelines was developed and tested. This index incorporated a woman's past and present use of mammography plus her future intent to be screened. Respondents were dichotomized into well-screened and not well-screened groups. Social and psychological factors associated with sustained screening as measured by this index were then explored. In bivariate analyses, education, health insurance, usual source of care, chronicity and preference for provider ethnicity and gender were significantly different for the two groups. In the multivariate model, women who were well-screened were significantly more likely to report recent physician contact, Pap smear, dental visit, history of breast problems, and beliefs that screening should be done annually and that early detection improves outcomes. Women reporting poor health were less likely to be well-screened. The well-screened index can potentially be used for assessment by clinicians and for program evaluation; however further validation studies need to be conducted. Despite limited resources, the majority of these urban African-American women are building lifetime patterns of regular breast cancer screening. Focused efforts are needed to achieve sustained screening patterns in the 25% who are not regularly screened.
We examined participation and dietary change among women participants in a community-based nutrition education program, to determine whether intervention results differed by participant body size. Four dietary indicators (daily servings of fruits and vegetables, total calories, calories from fat, and Healthy Eating Index score) were assessed from 24-h recalls taken before, immediately after, and 4 months after a seven-session nutritional education program, from 156 African-American women age 20-50, in Washington, D.C. public housing. Knowledge, attitudes and practices related to nutritional behavior change were collected at three time points as well. Random effect models were used to examine dietary patterns, and compare change by body size and class attendance. Results showed that obese women (BMI > or = 30) had more psychosocial barriers to dietary change and poorer baseline diets, but stronger program attendance. Post-intervention, both groups consumed approximately 250 fewer calories and 2.5% fewer calories from fat. At follow-up, non-obese women consumed significantly fewer calories; obese women consumed significantly fewer calories from fat, and showed significant improvement in HEI. Given the prevalence of obesity in low resource communities, nutritional interventions should tailor strategies to participant body size and related psychosocial needs.
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