Orbital vascular impedance reduction with orbital hyperperfusion was present in severe pre-eclamptic women compared with mild pre-eclamptic and healthy pregnant women. Ophthalmic Doppler is a novel parameter that may be useful in the diagnosis of severe pre-eclampsia.
OBJETIVO: O objetivo deste estudo é avaliar a variabilidade interobservador do método ultrassonográfico para medida da gordura subcutânea, visceral e perirrenal por meio de técnica padronizada. MATERIAIS E MÉTODOS: Foram avaliados 50 pacientes entre novembro de 2006 e janeiro de 2007. A medida da espessura subcutânea foi realizada com transdutor linear de 7,5 MHz posicionado transversalmente a 1 cm acima da cicatriz umbilical. Para a gordura visceral foi utilizado transdutor de 3,5 MHz posicionado 1 cm acima da cicatriz umbilical, considerando-se a medida entre a face interna do músculo reto abdominal e a parede posterior da aorta na linha média do abdome. A gordura perirrenal foi medida no terço médio do rim direito, com transdutor posicionado na linha axilar média. RESULTADOS: A reprodutibilidade interobservador foi analisada por meio do teste t de Student, com significância de 95%. Não houve diferença significativa entre as médias das medidas das gorduras subcutânea, visceral e perirrenal, com p = 0,7141, 0,7286 e 0,6368, respectivamente. As médias encontradas, com seus respectivos desvios-padrão, foram: 2,64 ± 1,37 para a espessura subcutânea, 6,84 ± 2,38 para a espessura visceral e 4,89 ± 2,6 para a espessura perirrenal. CONCLUSÃO: A ultrassonografia apresentou boa reprodutibilidade interobservador para avaliação da gordura abdominal por meio das medidas das espessuras subcutânea, visceral e perirrenal.
Oral communication abstracts(TVR < 1340 dyn · s · cm −5 , non concentric geometry of the left ventricle) for adverse outcomes of pregnancy. The differential diagnosis of hypertensive disorders in pregnancy is based in clinical, laboratorial and fundoscopic findings. The role of the ophthalmologist in the diagnosis of pre-eclampsia appears to be subjective and limited. Ophthalmic artery Doppler is an objective exam that can improve the diagnosis of hypertension in pregnancy. The study aims to analyze the ophthalmic artery Doppler indices in pregnancies with chronic hypertension and pre-eclampsia. Methods: Cross-sectional study that analysed 30 women with chronic hypertension and 44 preeclamptic women (National High Blood Pressure Education Program 2000 criteria) during the third trimester of pregnancy. Right and left eyes indices means and standard deviation were evaluated to the resistance index (RI), pulsatility index (PI), peak systolic velocity (PSV), end diastolic velocity (EDV) and peak ratio (PR). Mann-Whitney test were applied to compare the two groups of hipertensive woman and p-values < 0.05 were considerd statistically significant. Results: The ophthalmic arteries Doppler averages indices in chronic hypertension and pre-eclampsia were respectively RI: 0.74 ± 0.06; 0.63 ± 0.17, PI: 1.68 ± 0.41; 1.12 ± 0.28, PSV: 34.01 ± 10.3; 38.60 ± 9.67, DVF: 9.0 ± 4.12; 14.26 ± 4.74 and PR: 0.64 ± 0.13; 0.82 ± 0.09. The Doppler indices demonstrated ophthalmic artery lower impedance in preeclamptic women compared with chronic hypertension women. All the Doppler indices were accurate in the diferential diagnosis of chronic hypertension and pre-eclampsia demonstrated by p = 0.0001 (RI, PI, EDV, PR) and p = 0.0171 (PSV). The best parameter to establish a cut of point to differentiate chronic hypertension to pre-eclampsia was 0.75 to PR index. OC91 Ophthalmic artery Doppler in the differential diagnosis of hypertensive disorders in pregnancy Conclusions:The ophthalmic artery Doppler is a new parameter that can be used in the differential diagnosis and classification of hypertensive disorders in pregnancy. OC92A proposal for a pharmacological treatment for hypertensive pregnancies complicated by severe fetal growth restriction (FGR) with absent end diastolic flow (AEDF) of the umbilical artery University of Rome 'Tor Vergata', ItalyObjective: Evaluate the effect of nitric oxide (NO) donors and plasma volume expansion (PVE) added to antihypertensive therapy in gestational hypertensive (GH) pregnancies complicated by fetal growth restriction (FGR) with absent end-diastolic flow (AEDF) of Umbilical artery (UA). Methods: 32 GH pregnancies with FGR and AEDF were included into a case-control study. 16 were treated with antihypertensive drugs only (Group B), and 16 were added NO donors, and PVE to the antihypertensive treatment (Group A). All recruited patients underwent fetal and utero-placental assessment, and maternal echocardiographic evaluation calculating total vascular resistance (TVR) and cardiac output (CO) before and af...
Conjoined twins are the rarest type of monozygotic, monochorionic, monoamniotic twins, and have the incidence of 1:50000-1:100000 newborns. The prenatal diagnosis of conjoined twins allows better management of the multidisciplinary team associated with good parents counseling. The association of three-dimensional (3D) ultrasound and magnetic resonance imaging (MRI) to twodimensional (2D) ultrasound imaging can improve the diagnostic and classification of the twins malformations. We report two cases of thoraco-omphalopagus twins analyzed by 2D, 3D ultrasound and MRI, diagnosed during October 2005 and March 2006. First case: 28-years old woman G2P1 with 20 weeks spontaneous pregnancy, submitted to ultrasound with the diagnosis of conjoined twins. There was thoracoabdominal fusion with one umbilical cord formed by 2 arteries and one vein. There were two normal heads, with normal members and pelvics. The fetal heart was fused, with single atrium, two ventricles, valve anomaly, complex venous and arterial connection. It has been detected hepatic and diaphragmatic fusions and normal kidneys by ultrasound, confirmed by MR. Second case: 16-year old woman G1P0 with 22 weeks spontaneous pregnancy. She was submitted to ultrasound with the diagnosis of conjoined twins. The 3D and MR were performed to complement the diagnosis of organs fusion extension. There was thoracoabdominal fusion with one umbilical cord formed by 2 arteries and one vein. A complex fusion fetal heart, associated to hepatic and diaphragmatic fusion was detected. The superior and inferior members and heads were normal. The association of ultrasound 3D and MR improved the diagnostic and management of conjoined twins establishing the extension of organ sharing, by images not accessible by 2D ultrasound. It could also help the parents to understand better the kind of fetal fusion. The accurate diagnosis of conjoined twins is very important to determinate the fetal prognosis. P05.20 Three-dimensional ultrasonography and magnetic resonance imaging (MRI) of fetal malformation in monoamniotic twins Interregional Clinic Diagnostic Centre, Russian FederationObjective: Monoamniotic twins are frequently associate with other congenital anomalies such as conjoined twins and twin reversed arterial perfusion (TRAP). Our purpose is to improve clinical diagosis of monochorial twins using three-dimensional ultrasonography and MRI. Methods: Retrospectively we analyzed pregnancy results of 5 cases with monoamniotic twins. Two cases of 12-13 weeks we examined by 3D/4D-ultrasound (VOLUSON 730 EXPERT, GE) with surface rendering, volume rendering, Spatio Temporal Image Correlation and PW. Additionally we used MRI with T2 -weighted images and single shot fast spin echo in three-directions (Signa-Horizon, GE 1 Tesla) in three women on 20-21, 24 and 34 weeks of pregnancy. Results: In one case on the 20-21 weeks of pregnancy we have found conjoined twins with omphalothoracopagus and in another case of 12 weeks -omphalothoracopagus with brain herniation in one fetus. We had also two...
Breast cancer is the second leading cause of cancer death in women. Tomosynthesis is a new technique of additional exam that was created in order to improve the early detection of such disease. This technique shows a reconstructed image from different projections of the breast, reducing, this way, the effect of quantum noise due to the small thickness of the object of study. This paper aims at comparing the 3D reconstructed image with some filtered 2D polymethylmethacrylate (PMMA) images using structural similarity index (SSIM). We tested Wiener, Non-local Means, and Adaptive Median digital filters, which were applied at a region of interest of a 2D conventional mammography acquired in combo mode. From this work, we could quantify the level of similarity from different digital filters. Wiener and Adaptive Median filters increased the similarity between the 2D and the 3D tomosynthesis image, in terms of luminance, contrast and structure. However, the image with Nonlocal Means decreased significantly the similarity between the pair of compared images, proving the ineffective of this filter in reducing quantum noise.
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