The present study examined men and women's sexual and affective responses to erotic film clips that were combined with different fantasy instructions. Men (n = 29) and women (n = 28) were presented with two types of erotic films (explicit vs. romantic) and two fantasy instructions (fantasizing about one's real-life partner vs. fantasizing about someone else). Genital response, subjective sexual arousal, and affective responses were assessed. Sexually explicit stimuli resulted in larger genital responses; women reported higher subjective sexual arousal than men; and fantasizing about one's partner resulted, overall, in higher subjective sexual arousal and higher levels of positive affect. Moreover, in women, the instruction to fantasize about one's partner resulted in stronger subjective sexual arousal to the explicit film than the instruction to fantasize about someone else. Results suggested that physiological, subjective, and affective responses to erotic film stimuli are impacted not only by stimulus characteristics but also by the viewer's interpretation of the depicted relationship.

Introduction Cognitive schemas are often related to psychological problems. However, the role of these structures within sexual problems is not yet well established. Aim The aim of this study was to evaluate the presence and importance of early maladaptive schemas on women's sexual functioning and cognitive schemas activated in response to negative sexual events. Methods A total of 228 women participated in the study: a control sample of 167 women without sexual problems, a subclinical sample of 37 women with low sexual functioning, and a clinical sample of 24 women with sexual dysfunction. Main Outcome Measures Participants completed several self-reported measures: the Schema Questionnaire, the Questionnaire of Cognitive Schema Activation in Sexual Context, the Brief Symptom Inventory, the Beck Depression Inventory, and the Female Sexual Function Index. Results Findings indicated that women with sexual dysfunction presented significantly more early maladaptive schemas from the Impaired Autonomy and Performance domain, particularly failure (P < 0.001, η2 = 0.08), dependence/incompetence (P < 0.05, η2 = 0.03), and vulnerability to danger (P < 0.05, η2 = 0.04). Additionally, in response to negative sexual events, women with sexual dysfunction presented significantly higher scores on incompetence (P < 0.001, η2 = 0.16), self-depreciation (P < 0.01, η2 = 0.05), and difference/loneliness (P < 0.01, η2 = 0.05) schemas. Conclusions Results supported differences between women with and without sexual problems regarding cognitive factors. This may have implications for the knowledge, assessment, and treatment of sexual dysfunction in women.

Biofilms with induced dormancy were more likely to survive rifampicin. Furthermore, we found that the reduction of cultivable cells was not sufficient to reach definite conclusions on antimicrobial effectiveness.

Despite the increasing number of studies, it is not yet clear how emotions affect sexual response in women with and without sexual problems. The aim of this study was to explore the relation among trait-affect, depression, anxiety, and sexual functioning. Participants were 237 women: 167 without sexual problems, 37 with low levels of sexual functioning, and 17 with sexual dysfunction. Participants completed the Positive and Negative Affect Schedule, the Brief Symptom Inventory, the Beck Depression Inventory, and the Female Sexual Function Index. Results showed that women with sexual problems presented lower levels of positive trait-affect in comparison with women without sexual problems. Mediation analysis indicated that depression mediated 44% of the total effect of positive trait-affect and 83% of the total effect of negative trait-affect on sexual functioning. Moreover, anxiety (Brief Symptom Inventory subscale) mediated 18% of the total effect of positive trait-affect on sexual functioning and 61% of the total effect of negative trait-affect on sexual functioning. These results may help explain the high comorbidity among sexual dysfunction, depression, and anxiety, and raise the hypothesis that trait-affect may act as a common vulnerability factor for these clinical conditions.

Several studies highlighted the role of insula on several functions and in sexual behavior. This exploratory study examines the relationships among genital responses, brain responses, and eye movements, to disentangle the role played by the anterior and posterior insula during different stages of male sexual response and during visual attention to sexual stimuli. In 19 healthy men, fMRI, eye movement, and penile tumescence data were collected during a visual sexual stimulation task. After a whole-brain analysis comparing neutral and sexual clips and confirming a role for the bilateral insulae, we selected two bilateral seed regions in anterior and posterior insula for functional connectivity analysis. Single-ROI-GLMs were run for the FC target regions. Single-ROI-GLMs were performed based on areas to which participants fixate: “Faces”, “Genitals,” and “Background” with the contrast “Genitals > Faces”. Single-ROI-GLMs with baseline, onset, and sustained PT response for the sexual clips were performed. We found stronger effects for the posterior than the anterior insula. In the target regions of the posterior insula, we found three different pathways: the first involved in visual attention, onset of erection, and sustained erection; the second involved only in the onset of erection, and the third limited to sustained erection.