Fibroblasts are cells with a structural function, synthesizing components of the extracellular matrix. They are accordingly associated with various forms of connective tissue. During cardiac development fibroblasts originate from different sources. Most derive from the epicardium, some derive from the endocardium, and a small population derives from the neural crest. Cardiac fibroblasts have important functions during development, homeostasis, and disease. However, since fibroblasts are a very heterogeneous cell population no truly specific markers exist. Therefore, studying them in detail is difficult. Nevertheless, several lineage tracing models have been widely used. In this review, we describe the developmental origins of cardiac fibroblasts, comment on fibroblast markers and related lineage tracing approaches, and discuss the cardiac cell composition, which has recently been revised, especially in terms of non-myocyte cells.
8 March (8M), now known as International Women’s Day, is a day for feminist claims where demonstrations are organized in over 150 countries, with the participation of millions of women all around the world. These demonstrations can be viewed as collective rituals and thus focus attention on the processes that facilitate different psychosocial effects. This work aims to explore the mechanisms (i.e., behavioral and attentional synchrony, perceived emotional synchrony, and positive and transcendent emotions) involved in participation in the demonstrations of 8 March 2020, collective and ritualized feminist actions, and their correlates associated with personal well-being (i.e., affective well-being and beliefs of personal growth) and collective well-being (i.e., social integration variables: situated identity, solidarity and fusion), collective efficacy and collective growth, and behavioral intention to support the fight for women’s rights. To this end, a cross-cultural study was conducted with the participation of 2,854 people (age 18–79; M = 30.55; SD = 11.66) from countries in Latin America (Mexico, Chile, Argentina, Brazil, Peru, Colombia, and Ecuador) and Europe (Spain and Portugal), with a retrospective correlational cross-sectional design and a convenience sample. Participants were divided between demonstration participants (n = 1,271; 94.0% female) and non-demonstrators or followers who monitored participants through the media and social networks (n = 1,583; 75.87% female). Compared with non-demonstrators and with males, female and non-binary gender respondents had greater scores in mechanisms and criterion variables. Further random-effects model meta-analyses revealed that the perceived emotional synchrony was consistently associated with more proximal mechanisms, as well as with criterion variables. Finally, sequential moderation analyses showed that proposed mechanisms successfully mediated the effects of participation on every criterion variable. These results indicate that participation in 8M marches and demonstrations can be analyzed through the literature on collective rituals. As such, collective participation implies positive outcomes both individually and collectively, which are further reinforced through key psychological mechanisms, in line with a Durkheimian approach to collective rituals.
Objective: To evaluate the elderly persons' functionality, based on the International Classification of Functionality. Methods: a cross-sectional, descriptive study; a stratified random sample of 903 elderly persons; a confidence level of 95%; and a margin of error of 2.5%. Questionnaire based on the International Classification of Functionality; data was collected based on structured interviews undertaken by health professionals in the health centers in the Alentejo region of Portugal. Results: 30.7% of the elderly persons stated that they were illiterate, and 22.9% lived alone. Feeding/dietary (18.7%), housing (19.2%) and health needs (26.0%) were not met. Orientation functions were maintained in 83.4%; 58% of the elderly persons referred to pain so intense that it required care; 73.3% of the elderly persons did not have functional dentition. Levels of performance were superior to 80% in the participation activities: washing oneself (82.6%), toileting (92.2%), dressing, eating, and drinking (89%). Conclusion: although a progressive decline in functionality is observed as age advances, the majority of dimensions are preserved until around 75 years of age. Evaluación del funcionamiento y necesidades de cuidados de los ancianosObjetivo: Evaluar la funcionalidad de los ancianos basado en la Clasificación Internacional del Funcionamiento. Métodos: Estudio transversal, descriptivo; muestra aleatorizada, estratificada con 903 ancianos; nivel de confianza 95%; margen de error 2,5%. Cuestionario desarrollado basado en la Clasificación Internacional del Funcionamiento; datos recolectados a partir de entrevista estructurada por profesionales de salud en los Centros de Salud del Alentejo.Resultados: el 30,7% de los ancianos se declara analfabeto, 22,9% vive solo. Las necesidades de alimentación (18,7%), habitación (19,2%) y salud (26,0%) no están atendidas. Funciones de orientación preservadas en el 83,4%; el 58% de los ancianos indica una intensidad de dolor que demanda cuidados; el 73,3% de los ancianos no demuestra dentición funcional.Niveles de desempeño superiores al 80% en las actividades de participación: lavarse (82,6%), actividades relacionadas al proceso de excreción (92,2%), vestir, comer, beber (89%).Conclusión: Disminución progresivo del funcionamiento con el avance del edad, aunque sigue preservada grande parte de las dimensiones hasta acerca del edad de 75 años.Descriptores: Envejecimiento; Clasificación Internacional del Funcionamiento, de la Discapacidad y de la Salud; Evaluación de Necesidades.
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