PFAAs are rare but often occur with synchronous aneurysms. One-third of patients presented with complications of limb ischemia or rupture caused by their PFAA or synchronous aneurysms. Good-risk patients with a PFAA >2 cm should undergo elective repair. Aneurysmectomy with femoral interposition graft is a durable repair.
PAC-directed rapid right ventricular pacing is an effective method of inducing hypotension, enabling precise thoracic endograft deployment and safe balloon dilation after deployment. However, despite these advantages, the technique may be contraindicated in patients with severe valvular or ischemic heart disease.
The Publisher regrets that this article is an accidental duplication of an article that has already been published, doi: 10.1016/j.jvs.2011.10.003. The duplicate article has therefore been withdrawn.
pre-operatively and within 24 hours after carotid revascularization. Venous blood samples to assess serum levels of neuron-specific enolase (NSE) and S100 protein were collected for each patient pre-operatively and at five time points in a 24-hour post-operative period, and then assayed using automated commercial equipment. Relationship between serum markers levels and neuropsychometric and imaging tests and differences between the two groups of patients were analyzed by chi-square test with significance at pϽ0.05.Results: No TIA or strokes were clinically observed in the two groups. CAS caused more new subcortical lesions at post-operative DW-MRI (pϭ0.04) and a significant decline in MMSE post-operative score (pϭ0.045) compared to CEA. In CAS patients new lesions at DW-MRI were significantly associated with MMSE score decline greater than 5 points (pϭ0.03). Analysis of S100 and NSE levels showed a significant increase at 24 hours in CAS group compared to the CEA group (pϭ0.035).Conclusions: Biochemical markers measurements of brain damage combined with neuropsychometric tests and DW-MRI can be used to evaluate silent post-CAS injuries. In CAS the mechanisms of rise in S-100 and NSE levels at 24 hours may be due to increased peri-operative microembolisation rather than to hypoperfusion. Further studies are required to assess the clinical significance and cost effectiveness of those tests in carotid revascularization.Objectives: The contribution of hereditary and environmental factors to development of abdominal aortic aneurysms (AAA) is still unclear. The aim of this study was to analyze the role of these factors in a large populationbased sample of twins.Methods: The Swedish Twin Registry, containing data on twins born in the country since 1895, was cross-linked with the Inpatient Registry, providing national coverage of discharge diagnoses coded according to the International Classification of Diseases (ICD). All twins with an infrarenal AAA were identified. Concordance rates and tetrachoric correlations were calculated for monozygotic (MZ) and dizygotic (DZ) twins. Tetrachoric correlations were calculated for two normally distributed phenotypic variables that are both expressed as a dichotomy and reflect the similarity of twin pairs. Higher concordance rates and correlations of liability in MZ twins than in DZ twins suggest that genetic factors influence disease development. Structural equation modelling techniques, Mx-analyses, were used to estimate the contributions of genetic effects as well as shared and non-shared environmental factors for development of AAA.Results: There were 172890 twins registered at the time of the study including 266 twins (81% men; mean age 72 years, range 48-94) with AAA. There were 7 MZ and 5 DZ concordant pairs as wells 44 MZ and 197 DZ discordant pairs with AAA. The probandwise concordance rates for MZ and DZ pairs were 24% and 4.8%, respectively. The tetrachoric correlations were 0.71 in MZ pairs and 0.31 in DZ pairs. In the structural equation models, genetic effects accou...
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