The compound fac-[Ru((R)-BINAP)(H)(2-PrOH)3]+ (6) (BINAP = 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl) reacts with (R,R)-dpen (dpen = 1,2-diphenylethylenediamine) under H2 at -60 degrees C in 2-PrOH-d8/CD2Cl2 to generate the cationic dihydrogen putative intermediate trans-[Ru((R)-BINAP)(H)(eta2-H2)((R,R)-dpen)]+ (2') without H-D exchange between the hydrogen ligands and the solvent. A 1H NMR study concludes that the dihydrogen ligand in 2' does not protonate 2-PrOH to a catalytically significant extent, and that 2' requires an added base or hydride source to be an active catalyst.
Ruthenium catalysts of the form trans-RuCl2((R)-(S)-Josiphos)L2 where L2 = pyridine or 1,2-diamine, have been synthesized that display high catalytic activity towards the hydrogenation of 1'-acetonaphthone.
Enantioselective syntheses
Enantioselective syntheses O 0031 A Ruthenium Catalyst that Does not Require an N-H Ligand to Achieve High Enantioselectivity for Hydrogenation of an Alkyl ArylKetone. -Ruthenium catalysts of the form trans-RuCl 2 ((R)-(S)-Josiphos)L 2 (L: py or dpen) are synthesized that show high catalytic activity towards the enantioselective hydrogenation of 1-acetonaphthalene (I). -(LEONG, C. G.; AKOTSI, O. M.; FERGUSON, M. J.; BERGENS*, S. H.; Chem. Commun. (Cambridge) 2003, 6, 750-751; Dep. Chem., Univ. Alberta, Edmonton, Alberta T6G 2G2, Can.; Eng.) -M. Schroeter
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