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The number of women who would need to be screened regularly by mammography to prevent one death from breast cancer depends strongly on several factors, including the age at which regular screening starts, the period over which it continues, and the duration of follow-up after screening. Furthermore, more women would need to be INVITED for screening than would need to be SCREENED to prevent one death, since not all women invited attend for screening or are screened regularly. Failure to consider these important factors accounts for many of the major discrepancies between different published estimates. The randomised evidence indicates that, in high income countries, around one breast cancer death would be prevented in the long term for every 400 women aged 50–70 years regularly screened over a ten-year period.

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A novel method to obtain point correspondence in pairs of images is presented. Our approach is based on automatically establishing correspondence between linear structures which appear in images using robust features such as orientation, width and curvature extracted from those structures. The extracted points can be used to register sets of images. The potential of the developed approach is demonstrated on mammographic images.