Leptospirosis is a zoonotic bacterial infection that can cause influenza-like symptoms and severe disease. In Denmark, leptospirosis is rare, non-endemic, and most commonly transferred to humans from mice and rats. Cases of human leptospirosis in Denmark are by law notifiable to Statens Serum Institut. This study aimed to describe trends in incidence of leptospirosis in Denmark from 2012 to 2021. Descriptive analyses were used to calculate the incidence, geographical distribution and possible routes of infection, as well as testing capacity and serological trends. The overall incidence rate was 0.23 per 100,000 inhabitants, with the highest annual incidence of 24 cases in 2017. Men between 40-49 years old were the demographic group most commonly diagnosed with leptospirosis. August and September were the months with highest incidence over the entire study period. The most common serovar observed was Icterohaemorrhagiae, although over a third of cases were diagnosed via polymerase chain reaction alone. The most common sources of exposure reported were travel abroad, farming, and recreational contact with fresh water, the latter being a new exposure compared to previous studies. Overall, a One Health approach would ensure better detection of outbreaks and milder disease. Additionally, preventative measures should be expanded to include recreational water sports.

Background: Consumer Purchase Data (CPD) has emerged as a promising instrument to assess the impact of purchases on health. Here we describe a comprehensive prospective collection of CPD, the My Purchases cohort. The cohort included 428 participants as of April 18, 2023. Over eight years of CPD collected, 2,058,689 products were purchased, comprising 210,203 unique products. We matched 87.7% of all products by volume with nutrients, ingredients, or additives from at least one database. We found a median rate difference of 0.26 when we compared kilojoule information from generic and specific product matches. Further, increasing the number of retailers that provide CPD improved the stability of individual CPD profiles. Combined with extensive product databases and access to key health outcomes, CPD could approach a “consumerome” that could provide the basis for extensive investigations of how what we buy affects our health.

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