normal karyotype relate with negative screening for adverse perinatal results. Method: Retrospective study of cases and controls in single pregnancies, with predictive analysis using multivariate logistic regression. Results: 3,791 screenings were performed at our unit in 2012, with a screening/number of deliveries ratio of 89.9%. There is a greater likelihood of the newborn being underweight (AOR = 2.6, 95% CI 1.2 -5.7), premature (OR = 2.2, 95% CI 1. 03 -4.5), admitted to the ICU (OR = 7.4, or admitted to the Neonates department (AOR = 8.1, in the case group. Conclusion: Combined first trimester screening is a predictive method for pregnant women with a higher risk of adverse perinatal outcomes.
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