A strong greenish-light photoluminescence (PL) emission was measured at room temperature for disordered and ordered powders of CaMoO 4 prepared by the polymeric precursor method. The structural evolution from disordered to ordered powders was accompanied by XRD, Raman spectroscopy, and TEM imagery. Highlevel quantum mechanical calculations in the density functional framework were used to interpret the formation of the structural defects of disorder powders in terms of band diagram and density of states. Complex cluster vacancies) were suggested to be responsible to the appearance of new states shallow and deeply inserted in the band gap. These defects give rise to the PL in disordered powders. The natural PL emission of ordered CaMoO 4 was attributed to an intrinsic slight distortion of the [MoO 4 ] tetrahedral in the short range.
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Parkinson's Disease (PD) is the second most common neurodegenerative disease in the elderly
population, with a higher prevalence in men, independent of race and social class; it affects approximately
1.5 to 2.0% of the elderly population over 60 years and 4% for those over 80 years of age.
PD is caused by the necrosis of dopaminergic neurons in the substantia nigra, which is the brain region
responsible for the synthesis of the neurotransmitter dopamine (DA), resulting in its decrease in the
synaptic cleft. The monoamine oxidase B (MAO-B) degrades dopamine, promoting the glutamate accumulation
and oxidative stress with the release of free radicals, causing excitotoxicity. The PD symptoms
are progressive physical limitations such as rigidity, bradykinesia, tremor, postural instability and
disability in functional performance. Considering that there are no laboratory tests, biomarkers or imaging
studies to confirm the disease, the diagnosis of PD is made by analyzing the motor features.
There is no cure for PD, and the pharmacological treatment consists of a dopaminergic supplement
with levodopa, COMT inhibitors, anticholinergics agents, dopaminergic agonists, and inhibitors of
MAO-B, which basically aims to control the symptoms, enabling better functional mobility and increasing
life expectancy of the treated PD patients. Due to the importance and increasing prevalence of
PD in the world, this study reviews information on the pathophysiology, symptomatology as well as
the most current and relevant treatments of PD patients.
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