Smudge cells, also known as Gumprecht cells 1 are ragged lymphoid cells found mainly in peripheral blood smears of patients with chronic lymphocytic leukemia (CLL) and other B-cell chronic lymphoproliferative diseases (CLD). Smudge cells are not simply artifacts of slide preparations and there is Smudge cells in peripheral blood smears did not differentiate chronic lymphocytic leukemia from other B-cell chronic lymphoprolipherative diseases Sombras nucleares no esfregaço do sangue periférico não diferenciam a leucemia linfocítica crônica das outras doenças linfoproliferativas B crônicas
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