The change in immunological response obtained by immunobiologics has brought a new
paradigm to the treatment of immune-mediated disorders. As a result of their
efficacy, there is a positive impact on the quality of life of patients. However,
severe side effects, such as demyelination of cerebral or peripheral nerves, have
been reported. After review of literature using PubMed and MEDLINE data from 2000 to
2012, we identified the cases correlating the biological uniterms and optic neuritis.
This article reports the first Brazilian optic neuritis case associated with the use
of immunobiologics. This publication is justified by the rarity of the disease and
atypical therapeutical evolution.
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