Sphingomonas Paucimobilisis a gram negative bacilli (GNB). It has-been isolated in different places like water, soil, medications, dialysis fluids and hospital water systems. ITS, although pathogenic potential is mainly in immunocompromised hosts attributed, cases of severe infections in immunocompetent Patients have also been reported. Since its discovery, a large variety of infections such as, meningitis, endophthalmitis, peritonitis, septic arthritis, endovascular devices-related infections and so forth have been reported. Despite multiple severe infections have been described by this bacterium, the isolation of S. paucimobilis with multi resistance never had been reported. We report a case of endovascular device-related sepsis by carbapenemproducing S. paucimobilis (KPC) in a 64 years old female patient dialysis-dependent.