LAGB yielded substantial %EWL and a proportional decrease in plasma leptin. Our results support the hypothesis that LAGB works in part by suppressing the rise in ghrelin that normally accompanies weight loss. Unchanged concentrations of insulinotropic and digestive hormones suggest that gastrointestinal endocrine function is largely maintained in the long term.
Abnormal manometric findings are frequently encountered post-LAGB. Increases in LES residual pressure and peristaltic wave duration were the most significant changes. LAGB is not associated with an increase in total esophageal acidification time. Further evaluation of the clinical significance of manometric abnormalities is warranted.
Due to a production error, the following corrections were not incorporated into the text of the article (also in this issue) before it was published online. Springer regrets the error.Third page of the articlesecond columnunder BCharacteristics of the Study Population and %EWL after LAGB"-third paragraph:The paragraph should read,The Lap-Band surgery was successful; for the study population as a whole, %EWL was 31.2 (23.1-37.5) at 6 months and 45.7 (39.1-52.6) at 12 months after LAGB. BMI decreased significantly ( p < 0.001) from the baseline median of 43.2 (40.4-49.6) to 35.3 (33.9-40.3) at 6 months and 33.8 (30.9-37.7) at 12 months ( Fig. 1a; Supp Table 1).Fifth page of the articlesecond columnunder BInsulinotropic Hormone Levels in Relation to LAGB"first paragraphfirst sentence:The sentence should read, Before surgery, median (IQR), plasma concentrations (pg/ml) of insulin, GIP, and GLP-1 were 209 (144-419), 3.
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