In the rat experimental model, molar tooth movement induced by Waldo's method is known to cause a temporally and spatially defined pattern of brain neuronal activation. Since orthodontic correction usually involves the entire dental arch, we used a spring-activated appliance to extend the investigation to incisors, and we included brain regions related to antinociception. Adjustment of the non-activated appliance on incisors resulted in c-fos expression in the dorsal raphe, peri-aqueductal gray matter, and the locus coeruleus, in addition to trigeminal sensory subnuclei and the parabrachial nucleus, where neuronal activation has already been detected in previous studies on molar tooth movement. Appliance activation with a 70-g force resulted in a further increase in Fos-immunoreactive neurons in the trigeminal sensory subnucleus caudalis and in the dorsal raphe. This result suggests that there is a recruitment of neurons related to nociception and to antinociception when tooth movement is increased.
Resumo MAGDALENA, CMAP. Influência de diferentes técnicas de confecção da prótese ocular nas propriedades físicas, mecânicas, viabilidade celular e alteração de cor. Ribeirão Preto, 2018. 163p. Dissertação (Mestrado em
Surgical rehabilitation with grafts and plates of an oncological patient submitted to segmental mandibulectomy may be limited due to the majority receiving late diagnosis, requiring rapid intervention with association of drug therapies and thus, the risk of osteonecrosis. We detail a dental prosthetic rehabilitation in a patient who underwent a segmental mandibulectomy without plates or grafts. Man, 47-years old, affected by a squamous cell carcinoma on the floor of the mouth, treated by segmental mandibulectomy, radiotherapy and chemotherapy, was attended to a dental prosthetic rehabilitation over the mandible segments with a removable partial denture. Initially, a temporary prosthesis was made, in order to adapt the patient with the restoration of the occlusion and recovering the muscle tone. The patient used the temporary removable partial denture for 6 months, accompanied by physical therapy to maintain occlusal stability and regain muscle tone. After this period, it was possible to make a removable partial denture for definitive rehabilitation. The patient proved to be adapted to the prosthetic device and satisfied with the treatment. Prosthetic rehabilitation is a viable option when surgical reconstruction is contraindicated or can be used until the surgical procedure can be realized.
This study evaluated the effect of different drying time of iris paint/paint protection agent, iris inclusion substrates, and passage of time on iris color change. The 120 specimens were divided into six groups (n = 20) according to the drying time (24hr or 1hr)/iris protection agent (cyanoacrylate, cyanoacrylate + polymer; monopoly + polymer). After, the groups were divided into subgroups (n = 10) as a function of the inclusion substrate (wax or thermopolymerizable acrylic resin N1). Acrylic caps were painted with Black, Sepia, and Vandik brown acrylic paint. After the drying time, the irises received a layer of the protection agent and after drying, they were submitted to the first color reading (EasyShade -lighting D65). A sclera pattern was included to obtain sclera in wax and N1 acrylic resin, in which the irises were included and processed. After seven days, the color measurements were performed, the prosthesis were stored in a container with water at 37ºC for new readings after 14, 30 and 90 days. Data were analyzed by factorial ANOVA test repeated (p<0.05). The passage of the time significantly influenced the color change of the specimens (p<0.001), with the greatest color variation occurring in the first 7 days. The type of protection agent, drying time and iris inclusion substrate not influenced the color change. The greatest change in color was observed after 7 days, and remained unchanged over 90 days, although the values were considered clinically perceptible.
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