Edentulous patients have reported difficulties in managing complete dentures; they have also reported functional concerns and higher expectations regarding complete dentures than the dentists who have treated them. Some of the objectives of definitive fixed implant prosthodontic care include predictable, long-term prostheses, improved function, and maintenance of alveolar bone. One of the keys to long-term clinical success is the design and fabrication of metal frameworks that support implant prostheses. Multiple, diverse methods have been reported regarding framework design in implant prosthodontics. Original designs were developed empirically, without the benefit of laboratory testing. Prosthetic complications reported after occlusal loading included screw loosening, screw fracture, prosthesis fracture, crestal bone loss around implants, and implant loss. Numerous authors promoted accurately fitting frameworks; however, it has been noted that metal frameworks do not fit accurately. Passively fitting metal implant frameworks and implants have not been realized. Biologic consequences of ill-fitting frameworks were not well understood. Basic engineering principles were then incorporated into implant framework designs; however, laboratory testing was lacking. It has been reported that I- and L-beam designs were the best clinical option. With the advent of CAD/CAM protocols, milled titanium frameworks became quite popular in implant prosthodontics. The purpose of this article is to discuss current and past literature regarding implant-retained frameworks for full-arch, hybrid restorations. Benefits, limitations, and complications associated with this type of prosthesis will be reviewed. This discussion will include the relative inaccuracy of casting/implant fit and improved accuracy noted with CAD/CAM framework/implant fit; cantilever extensions relative to the A/P implant spread; and mechanical properties associated with implant frameworks including I- and L-beam designs. Guidelines will be proposed for use by clinicians and laboratory technicians in designing implant-retained frameworks.

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Immediate occlusal loading of multiple, splinted mandibular implants is an effective treatment when implants are stable at insertion and are rigidly splinted with implant-retained prostheses.

Osseointegration may be most dependent on anatomical location in the jaws.