Oral candidiasis is an oral mucosal infection caused by Candida albicans (CA) ornon-Candida albicans Candida (NCAC). C. tropicalis (CT) is most virulent NCACbecause it has the most adherence ability to epithelial cells in vitro as well as mediumlevel proteinase secretion. In addition, CT is the second most common colony found inhuman. Although incidence rate of oral infection was low, this species has virulencepotency, lately reported as the mayor cause of candidemia in immunocompromisedpatients. This paper reports and discusses oral candidiasis due to CT in a child whosuffered anemia with clinical sign of malnutrition. Oral nystatin suspension is therapyof choice because of patient well response, and in vitro studies reported lack ofresponse of fluconazole to candidemia due to C.tropicalis. However, nystatin oralsuspension, should be synchronized with hygiene optimalization of elimination ofpredisposition factors, and supportive therapy would provide a good prognosis.
Background: In 2019, a viral disease spread from Wuhan, Hubei Province in China. The disease was caused by severe acute respiratory syndrome related to coronavirus 2 (SARS-CoV-2 virus), which was named by the Coronavirus Study Group of the International Committee on Taxonomy of Viruses. Purpose: This article reports the multi-discipline treatment of Covid tongue and exfoliative cheilitis with a main diagnosis of bilateral pneumonia caused by SARS-CoV-2 infection. Case: A female patient, 70 years old was referred with a diagnosis of bilateral pneumonia by a pulmonologist. She complained of painful wounds all over her mouth. An intraoral clinical examination revealed white-thick lesion and multiple ulcerations, whilst an extraoral exam for exfoliative dermatitis has not been described. The working diagnosis was Covid tongue mixed with exfoliative cheilitis. Case management: The procedure was performed by teledentistry and direct visits to implement oral health care by asepsis, debridement and the application of Oxygene gel. Conclusion: The lesion was treated successfully due to the multidisciplinary approaches by an internist and pulmonologist by implementing integrated knowledge and was supported hugely by patient cooperation.
Oral candidiasis is oral mucosal infectious caused by Candida albicans or non-candida albicans candida (NCAC).Each Candida species infection has same clinical manifestation, the different only in invasive nature and antifungiresponse. C.tropicalis is most virulence NCAC because the most adherence ability to epithelial cells in vitro as wellas medium level proteinase secretion. In addition, C.topicalis is the second most common colony on human. A studyreported of C.tropicalis as causa of 16% hospitalized oral candidiasis, anti fungal drugs and systemic antibioticwas known as trigger factors. This paper report and discuss oral candidiasis due to C.tropicalis in patient, adultmale, with median rhomboid glossitis. The patient also used broad spectrum antibiotic and topical corticosteroidwith imprecise dose. The management of this case was terminated antibiotic and corticosteroid, oral hygieneoptimalization and was given 0.25% chlorhexidine gluconate. However, oral hygiene optimalization, predispositionfactors elimination, and, precise therapy would give a good prognosis.
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