This study allows the discovery of role interaction models through the use of real-life clinical data and process mining techniques. Results show a useful way of providing relevant insights about how healthcare professionals collaborate, uncovering opportunities for process improvement.
Type 2 Diabetes Mellitus (T2DM) is a chronic disease that has risen in prominence in recent years and can cause serious complications. Several studies show that the level of adherence to different types of treatment has a direct correlation with the positive evolution of chronic diseases. While such studies relate to patient adherence to medication, those that concern adherence to medical appointments do not distinguish between the different disciplines that attend to or refer patients. This study analyses the relationship between adherence to referrals made by three distinct disciplines (doctors, nurses, and nutritionists) and the results of HbA1c tests from a sample of 2290 patients with T2DM. The aim is to determine whether a relationship exists between patient improvement and the frequency with which they attend scheduled appointments in a timely manner, having been previously referred from or to a particular discipline. Results showed that patients tended to be more adherent when their next appointment is with a doctor, and less adherent when it is with a nurse or nutritionist. Furthermore, patients that remained stable had higher rates of adherence, whereas those with lower adherence tended to be more decompensated. The results can enable healthcare professionals to monitor patients and place particular emphasis on those who do not attend their scheduled appointments in a timely manner.
Objectives: We aimed to evaluate QoL and Ut in DM2 patients receiving vildagliptin or sulphonylureas (SU) add-on to metformin therapy in a real-world setting. MethOds: In the whole, 229 DM2 patients (mean age -61.3±9.5 years, 68.1% females) receiving vildagliptin add-on to metformin/GalvusMet (Group 1, n= 104) or SU add-on to metformin (Group 2, n= 125) were enrolled in the real-world multicenter observational study. Mean disease duration was 5.9±4.1 years, mean HbA1с level -6.9%±0.8%, late complications were revealed in 27.5% of patients, comorbidities -in 64.6%. All the patients completed SF-36 questionnaire. The Ut scores were calculated for each patient on the basis of SF-6D questionnaire. The SF-6D utility indexes were obtained from SF-36 data. The mean Ut for each treatment group was calculated with adjustment for gender, age, comorbidities, late complications and HbA1с level. Group comparisons were made using General linear models with adjustment for age, comorbidities and late complications. Results: It was shown that patients in Group 1 had higher QoL by the majority of SF-36 scales: role physical functioning -74.3 vs 50.3; bodily pain -82.9 vs 69.1; general health -56.5 vs 47.7; vitality -64.4 vs 56.0; social functioning -83.7 vs 72.5; role emotional functioning -86.1 vs 58.4 (p< 0.05). Integral QoL Index in Group 1 was higher -0.525 vs 0.351 (p< 0.001). The significant difference between Ut values for two groups was revealed: the mean Ut for Group 1 was higher as compared to mean Ut for Group 2 -0.757 vs 0.701 (p< 0.05). cOnclusiOns: Results of this real-world study demonstrate benefits of treatment with vildagliptin add-on to metformin/GalvusMet in DM2 patients as compared to SU add-on to metformin in terms of better QoL and higher health utility. The data obtained may be used for cost-utility analysis and be further applied for health technology assessment. PDB76 eu5 Patient's willingness to tRy new tecHniQues foR Managing tHeiR DiaBetes MellitusObjectives: Diabetes Mellitus is a large and growing condition in the EU5, prevalence ranges from 4.8% in Italy to 8.9% in Germany. The total direct cost of diabetes in the EU5 was € 90 Billion (2010). The management of diabetes is a growing concern given the already high prevalence and associated high costs. As we seek to improve the management of diabetes, it's important to integrate patient preferences into policy and market access decisions. MethOds: The 2014 EU Roper Diabetes Study was conducted among 3,013 diagnosed adult diabetes patients across the EU5. During 50-min telephone interviews, respondents were asked about their willingness to investigate new techniques and preferences for managing their diabetes. Data were compared across countries, diabetes type, age group, year since diagnosis and current therapy to determine relative openness to new techniques. Statistical significance testing between analytic groups was performed at the 95% confidence level. Results: In total 46.9% of diabetes patients reported that they would "like to investigate or t...
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