ObjectiveThe purpose of our study was to evaluate the association between short and long sleep duration and all-cause and cardiovascular mortality among elderly individuals.DesignSystematic review and meta-analysis of population-based cohort studies.SettingArticles were retrieved from international and national electronic databases.Study selectionStudies were identified in PubMed, EMBASE, LILACS (Latin American and Caribbean Health Sciences Literature), IBECS (Bibliographic Index on Health Sciences from Spain) and CAPES (PhD thesis repository) between 1980 and 2015. Studies which met all criteria were eligible: participants aged 60 years or over, assessment of sleep duration as 24 h, nighttime or daytime sleep, evaluation of all-cause or cause-specific mortality, population-based cohort studies conducted on representative samples. There was no language restriction and studies published as abstracts were excluded.Data extractionData were analysed using the Comprehensive Meta-Analysis software (V.3.3.070), and summary estimates (relative risk (RR), 95% CI) were calculated using a random effects model. Heterogeneity and consistency were evaluated through Cochran's Q and the I2 statistics, respectively, and sensitivity analyses were conducted.Primary and secondary outcome measuresAll-cause and cardiovascular mortality.ResultsOverall, 27 cohort studies were selected, comprising >70 000 elderly individuals, and followed up from 3.4 to 35 years. In the pooled analysis, long and short sleep duration were associated with increased all-cause mortality (RR 1.33; 95% CI 1.24 to 1.43 and RR 1.07; 95% CI 1.03 to 1.11, respectively), compared with the reference category. For cardiovascular mortality, the pooled relative risks were 1.43 (95% CI 1.15 to 1.78) for long sleep, and 1.18 (95% CI 0.76 to 1.84) for short sleep. Daytime napping ≥30 min was associated with risk of all-cause mortality (RR 1.27; 95% CI 1.08 to 1.49), compared with no daytime sleep, but longer sleep duration (≥2.0 h) was not (RR 1.34; 95% CI 1.95 to 1.90).ConclusionsAmong elderly individuals, long and short sleep duration are associated with increased risk for all-cause mortality. Long sleep duration is associated with cardiovascular mortality.
ObjectiveTo evaluate the functional status of pediatric patients after discharge from
the pediatric intensive care unit using the Functional Status Scale and to
compare the time of invasive mechanical ventilation, length of stay in the
pediatric intensive care unit, and Pediatric Index of Mortality 2 results
among individuals with different degrees of functional impairment.MethodsA cross-sectional study was conducted on patients who were discharged from a
pediatric intensive care unit. The functional evaluation by the Functional
Status Scale was performed on the first day after discharge from the unit,
and the Pediatric Index of Mortality 2 was used to predict the mortality
rate at the time of admission to the pediatric intensive care unit.ResultsThe sample consisted of 50 individuals, 60% of which were male, with a median
age of 19 [6 - 61] months. The overall score of the Functional Status Scale
was 11.5 [7 - 15], and the highest scores were observed in the "motor
function" 3 [1 - 4] and "feeding" 4 [1 - 4] domains. Compared to patients
who were not readmitted to the pediatric intensive care unit, patients who
were readmitted presented a worse overall score (p = 0.01), worse scores in
the "motor function" (p = 0.01), "feeding" (p = 0.02), and "respiratory" (p
= 0.036) domains, and a higher mortality rate according to the Pediatric
Index of Mortality 2 (p = 0.025).ConclusionEvaluation of the functional status using the Functional Status Scale
indicated moderate impairment in patients after discharge from the pediatric
intensive care unit, mainly in the "motor function" and "feeding" domains;
patients who were readmitted to the pediatric intensive care unit
demonstrated worse overall functional, motor function, feeding and
respiratory scores. Individuals with greater functional impairment had
longer times of invasive mechanical ventilation and hospitalization in the
pediatric intensive care unit.
Background: Despite the increasingly careful attempts to reduce perioperative risks, pulmonary complications following surgery are still very common, leading to longer length of hospital stays or death.
The prevalence of excessive screen time and TV viewing was high among Brazilian adolescents. Intervention are needed to reduce the excessive screen time among adolescents.
Desafios para a coleta de sangue e análise bioquímica em um grande estudo multicêntrico realizado em escolas com adolescentes: lições do ERICA no Brasil Desafíos para la recolección de sangre y el análisis bioquímico en un gran estudio multicéntrico con adolescentes en las escuelas: lecciones del ERICA en Brasil
BackgroundExcessive screen time has been associated with metabolic syndrome (MetS) among adolescents; however, snack intake in front of screens may play a role in this association. Therefore, our objective was to investigate the association between screen-based sedentary time with MetS and whether this association is modified by unhealthy snack intake in front of screens.MethodsThis study was a nationwide, cross-sectional, school-based survey in Brazil including adolescents aged 12 to 17 years. The frequency of snack consumption in front of screen and screen-based sedentary time (TV view, computers and videogames use) were self-reported. Thereafter, screen time was categorized (≤2, 3–5 and ≥ 6 h/day); snack consumption in front of screens was dichotomized. Metabolic syndrome diagnosis was defined based on the International Diabetes Federation criteria. Associations between screen time and MetS were investigated using logistic regression in overall sample and after stratification by snack intake in front of screens.ResultsA total of 33,900 adolescents were included in the analysis. The final adjusted model, which included sociodemographic data, physical activity, and energy intake, showed that adolescents who spent ≥6 h/day in front of screens had an increased odds ratio for MetS (OR = 1.68, 95%CI: 1.03–2.74). However, after stratifying the sample according to reported snack intake, the association between higher screen-based sedentary time and MetS remained significant only for adolescents who reported consumption of snacks in front of screens.ConclusionLonger screen-based sedentary times were directly associated with MetS. However, this association seems to be modified by reported snack intake in front of screens.
The systematic reviews of interventions to prevent or reduce obesity in children and adolescents generally showed little or no effects on weight or body mass index, although cardiovascular profile can be improved. Mixed interventions demonstrated better effects, but the long-term impact of obesity treatments of children and adolescents remains unclear.
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