Image enhancement technology is often used to improve the quality of medical images and helps doctors or expert systems identify and diagnose diseases. This paper aimed at the characteristics of magnetic resonance imaging (MRI) with complex and difficult-to-enhance details and to propose a nonsubsampled contourlet transform- (NSCT-) based enhancement algorithm called MIE-NSCT. NSCT was used for MRI sub-band decomposition. For high-pass sub-bands, four fuzzy rules were proposed to enhance multiscale and multidirectional edge contour details from adjacent eight directions, whilst for low-pass sub-bands, a new adaptive histogram enhancement algorithm was proposed. The problem of noise amplification and loss of details during the enhancement process was solved. The algorithm was verified on the public dataset BraTS2017 and compared with other advanced methods. Experimental results showed that MIE-NSCT had obvious advantages in improving the quality of medical images, and high-quality medical images showed enhanced performance in grading tumour. MIE-NSCT is suitable for integration into an interactive expert system to provide support for the visualization of disease diagnosis.
The use of medical image synthesis with generative adversarial networks (GAN) is effective for expanding medical samples. The structural consistency between the synthesized and actual image is a key indicator of the quality of the synthesized image, and the region of interest (ROI) of the synthesized image is related to its usability, and these parameters are the two key issues in image synthesis. In this paper, the fusion-ROI patch GAN (Fproi-GAN) model was constructed by incorporating a priori regional feature based on the two-stage cycle consistency mechanism of cycleGAN. This model has improved the tissue contrast of ROI and achieved the pairwise synthesis of high-quality medical images and their corresponding ROIs. The quantitative evaluation results in two publicly available datasets, INbreast and BRATS 2017, show that the synthesized ROI images have a DICE coefficient of 0.981 ± 0.11 and a Hausdorff distance of 4.21 ± 2.84 relative to the original images. The classification experimental results show that the synthesized images can effectively assist in the training of machine learning models, improve the generalization performance of prediction models, and improve the classification accuracy by 4% and sensitivity by 5.3% compared with the cycleGAN method. Hence, the paired medical images synthesized using Fproi-GAN have high quality and structural consistency with real medical images.
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