Abstract:Objective: Assess the profile of eye drops in patients with eye diseases. Methods: Studies available in the scientific literature were identified without any time limits using the databases Embase-Medline, Scielo, Scopus and Web of Knowledge. The selected studies were compared with the following inclusion criteria: (i) if the study evaluated the eye drop instillation, (ii) if the study involved participation of patients with eye diseases. Results: Twelve studies met the inclusion criteria. Of them, 83.33% evaluated the technique of eye drop instillation in patients with glaucoma, 8.33% in patients with eye diseases and 8.33% in patients with cataract after undergoing surgery to correct. 41.66% of studies have chosen to record a video of patients to analyze the technique of instilling eye drops and 41.66% did not describe the/esearch location. Regarding the type of study, 75% had the design as prospective cross-sectional, 8.33% prospective open label study, 8.33% intervention study and 8.33% study called masked trial. Although studies evaluate the technique of eye drop instillation, only 8.33% describe in the article the reference in the literature used to evaluate patients. 50% of articles acknowledged some sort of bias or limitation. Conclusion: The limitations inherent in these types of studies should guide future research.
Glaucoma is a major public health problem, being the leading cause of irreversible visual impairment worldwide. In most cases, glaucoma is associated with intraocular pressure (IOP) levels that are above those considered normal (IOP ≥ 21 mmHg). The aim of the present work is to describe the pattern of eye drops prescription in patients with glaucoma in the state of Sergipe, Brazil. A descriptive crosssectional study with retrospective documentary analysis, developed at the Eye Institute of Sergipe was performed. Of all glaucoma patients, 41.5% had a family history of the disease. Among the popular drugs, Latanoprost 0.005% is the most requested totaling 34% of prescriptions. In the Region 2, a significant association ( 2 = 48, 45; p<0.05) was observed between monotherapy and high IOP. The present study showed that the pattern of eye drops prescription was as recommended by the Brazilian Society of Glaucoma. Although, these medications were distributed freely, most patients with glaucoma have high IOP. Therefore, considering the importance of glaucoma as the second cause of blindness worldwide it is essential to carry out studies that evaluate the factors that influenced the effectiveness of eye drops use for treatment of glaucoma.
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