Sodium alginate was hydrophobically modified by coupling of polybutyl methacrylate onto the alginate. The polybutyl methacrylate was previously prepared through polymerization of butyl methacrylate in the presence of 2-amino-ethanethiol as a chain transfer agent. The structure of the product was characterized by Fourier-transformed infrared spectrometry, nuclear magnetic resonance ((1)HNMR) and thermogravimetry. The result of fluorescence analysis showed that the hydrophobicity of the modified alginate was obviously increased. The modified alginate conjugate was used for immobilization of bovine serum albumin in the presence of calcium chloride. In addition, the release behavior of the drug-loaded alginate in deionized water and Tris-HCl buffer solution (pH 7.2) was investigated. It was found that the modified sodium alginate possessed prolonged release behavior compared to unmodified sodium alginate, and it had potential application in controlled release as a drug carrier.
The unified approach based upon the Reduced Reynolds technique is applied to develop a deterministic transient mixed lubrication line contact model. This model is used in spur gear applications to comprehensively show effects of roughness, working conditions, i.e., rotational speeds and loads on pressure ripples and severity of asperity contacts. Results show effects of the speed, the load, as well as the RMS value are coupled which makes it difficult to evaluate lubrication states by only considering one variable. Considering the Ree-Eyring non-Newtonian behavior could alleviate pressure ripples significantly, compared with the Newtonian fluid assumption. Small RMS values of surfaces, which could be achieved by superfinish techniques, would be desirable when evaluating gear tooth surface contact performances.
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