The palladium-catalyzed decarboxylative ortho-acylation of O-methyl ketoximes with α-oxocarboxylic acids in the presence of Na 2 S 2 O 8 and Ag 2 O is demonstrated. This protocol can be applied to various O-methyl ketoximes and α-oxocarboxylic acids with both electron-donating and electron-withdrawing groups with products yields up to 98%.
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