IntroductionOur aim was to evaluate different treatment methods including conservative treatment (CT), locking-plate osteosynthesis (OS) and hemiarthroplasty (HA) in three-and four-part humeral fractures in patients older than 50 years. MethodsForty-seven patients that have at least one year of follow-up were divided into three groups: 18 patients treated with OS, 14 patients treated conservatively and 15 patients treated with HA. For further evaluation, constant shoulder score, disabilities of the arm, shoulder and hand score (DASH), American Shoulder and Elbow Society (ASES) score had been used. Shoulder range of motion was also assessed. ResultsOS and CT groups had better scores than HA group. In OS group, average Constant score was 71.6 ± 16.2, DASH score was 12.1 (5.2-24.2) and ASES score was 77.5 (50.8-96.6). In CT group, average Constant score was 69.6 ± 19.2, DASH score was 16.4 (12.5-36.7) and ASES score was 76.6 (45.4-87.9). DASH scores (p = 0.032), Constant scores (p = 0.001), forward elevation (p < 0.001), abduction (p < 0.001), internal (p = 0.022) and external rotation (p = 0.048) were significantly improved in OS and CT groups than HA group. ConclusionsHA should not be considered a priority in surgical planning in Neer three-part and four-part proximal humerus fractures. CT is superior for patients with additional morbidity and advanced age. But in patients who are younger and can tolerate the surgical procedure, the priority should be OS.
BackgroundWe aimed to report the clinical and electrophysiological results of patients who were treated with an endoscopically assisted in situ release technique for cubital tunnel syndrome and to show safety and efficacy of this procedure.Materials and methodsTwenty nine patients were included into the study. 13 patients (44.8%) were female, 16 patients (55.2%) were male. The mean age was 44.4 years (range; 22–66 years). Mean follow up period was 16.0 months (range; 7–42 months). We used Dellon classification for preoperative staging, and modified Bishop rating system for the evaluation of postoperative clinical results. Dynamometric and electromyographic measurements were obtained preoperatively and at final control.ResultsPreoperative Dellon's classification revealed 3 patients grade 1, 14 grade 2, and 12 grade 3. Modified Bishop score was very good for 21 patients (72.4%), good for 4 patients (13.8%), fair for 3 patient (10.3%), and poor for 1 patient (3.4%). At final control; the mean proportion of grip power and pinch strength of the affected hand to the contralateral normal hand was improved, and also nerve conduction velocity were improved in all patients. As complication, hematoma formation developed in two cases.ConclusionOur study showed that endoscopically assisted decompression technique without using any special instruments can be performed successfully with a low complication rate. It is a safe and effective method in the treatment of cubital tunnel syndrome.Level of evidenceLevel IV, Therapeutic study
Article HistoryReceived 05 / 02 / 2013 Accepted 11 / 02 / 2013A 30 days old healthy male infant with left thigh swelling was presented to our clinic by his family. Parents gave no history of diseases or trauma and was administered hepatitis B vaccine from left thigh one week before. Physical exam revealed approximately 3x2 cm, erythematous, indurated, tender to palpation, fluctuating soft tissue swelling over the anterolateral left thigh. During needle puncture, 15 cc purulent liquid was aspirated. As the liquid was purulent, irrigation and debridement were performed. Following six weeks of antibiotic treatment, the patient was completely recovered.
Article HistoryThe difference between the highest temperature observed in the postoperative period and the temperature in the preoperative period was calculated and termed as delta temperature. The delta temperature in the arthroscopically treated group was found 1.2± 0.7 o C and was 0.8±0.5 0 C in the other group (p<0.05). Time, gender and diagnosis were not a risk factor in the increase in the subfebrile temperature postoperatively. But the method of surgical treatment was found as a risk factor in the increase in subfebrile body temperature (p<0.021). We have seen increase in the subfebril temperature in both arthroscopically alone and arthroscopic+mini-open treated patients but the rise in the subfebrile temperature was higher in the arthroscopically treated patients compared with the other group. The surgical method whether arthroscopy or arthroscopic+mini-open is a risk factor for an increase in post operative temperature.
SUMMARYObjective: The aim of this study was to investigate the effect of pentoxifylline (PNX) with a pharmacological dose range on proliferation of human umblical venous endothelial cells (HUVEC). Method: The cells were maintained in M199 supplemented with 20% fetal bovine serum, penicillin, and streptomycin. The cultures were cultivated in an incubator at 37°C and with 5% CO2, until cell monolayers attained confluence which occurred after 7 days. The assays were performed in the exponential growth phase of the cells. The cell viability was assessed using the cleavage of tetrazolium salts added to the culture medium. Pentoxifylline with concentrations of 10 -4 M, 10-5M, 10 -6 M and 10 -7 M were used for the proliferation assay in which cells were incubated for 24, 48, and 72-hours with these drugs. The experiments were conducted in six replicates. Results: Only the 10 -4 M dose of PNX at 72 h significantly reduced the viability of HUVEC (p<0.05) and except this, there was no cytotoxic effect of PTX on HUVEC in a dose-and time-dependent manner (p>0.05). Conclusions: Overall, PTX with a pharmacological dose range has no cytotoxic effect on HUVEC. We think that this is also in accordance with the findings of several studies performed in animal models and clinical settings, indicating positive effects of PTX on tissues in normal and ischemic conditions. Keywords: Pentoxifylline, proliferation, human umbilical venous endothelial cells ÖZET Amaç: Bu çalışmanın amacı farmokolojik doz aralığında uygulanan pentoksifilinin insan umblikal ven endotel hücrelerinin (HUVEC) proliferasyonu üzerine etkisini araştırmaktır. Yöntem: Hücreler içerisine %20 fetal bovine serum, penisilin ve streptomisin eklenen M199 besiyeri içinde, %5 CO2 içeren 37 C 'lik inkübatörde kültüre edildi. Deneyler hücreler gelişim fazında iken gerçekleştirildi. Hücrelerin canlılığı kültür ortamına tetrazolium tuzları eklenerek değerlendirildi. Pentoksifilinin 10 -4
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