The chromosomes of tragelaphine antelopes studied to date are reviewed. All males of the six species of the tribe thus far investigated show the presence of a Y-to-autosome fusion.It is postulated that the fusion found in the six species had its origin in a common ancestor.Based on results in present-day species, an interpretation of the possible events in the evolution of the chromosomes of species so far studied is set out.The hypotheses put forward on the evolution of tragelaphine chromosomes are testable in that banding techniques done on more suitably prepared chromosomes can now examine more critically the re-arrangements identified and postulated in this publication. It is stressed that such banding studies are necessary in members of the tribe to provide further elucidation of the mechanisms of chromosomal evolution in the tribe.
This study describes 12 examples of translocations between chromosomes 7 and 14 in short-term peripheral blood lymphocyte cultures from 10 patients investigated in a routine cytogenetic series. Only one constant breakpoint was found on 14q, and chromosome 7 had two constant breakpoints, one on 7p and the other on 7q. The cause and true significance of such nonrandom in vitro chromosome translocations is not known at present, but one may speculate as to their possible indication of heterozygosity for a chromosome instability syndrome and thus a predilection for the development of lymphoid or other malignancy.
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