With the explosive growth of the dietary supplements industry, new demands have emerged that cannot be faced with the sophisticated instrumentation available in well-equipped laboratories. In particular, there is a demand for simplified and easy-to-use instruments, capable of providing results in short times of analysis. In this study, a hand-portable miniaturized liquid chromatograph (portable LC) has been tested for the determination of chlorogenic acids (CGAs) in products intended to supplement the diet and elaborated with green coffee extracts. CGAs offer several health benefits due to their antioxidant properties, and an increasing number of dietary supplements are marketed with claimed high contents of these compounds. The results obtained with the proposed portable LC approach have been compared with those obtained with two other miniaturized benchtop liquid chromatography instruments, namely, a capillary liquid chromatograph (capLC) and a nano liquid chromatograph (nanoLC). Although compared with the methods that used the benchtop instruments, the sensitivity attainable was lower, the portable LC instrument provided a comparable analytical performance for the quantification of the main GCAs at low mg g−1 levels, and it was clearly superior in terms of speed. The proposed portable LC-based method can be applied to assess the content and distribution profile of the predominant CGAs in this kind of dietary supplement. It can be also used to estimate the antioxidant power due to CGAs, as well as their preservation state.
inDicaDoREs DE saluD bucal DE la comuna DE las guaitEcas E islas huichas, REgión DE aysén oral healTh indicaTors of las guaiTecas MunicipaliTy and huichas islands, aysen region, chileREsumEn Objetivo: Debido a la falta de información epidemiológica sobre salud bucal en la egión de Aysén y zonas aisladas de nuestro país, es que el objetivo de este estudio es evaluar los indicadores de salud bucal dependientes del COPD y ceod en la comuna de Las Guaitecas e Islas Huichas.Materiales y Métodos: Un total de 104 fichas odontológicas fueron consideradas en el estudio; 63 correspondientes a Guaitecas y 41 a Islas Huichas. 43 del programa de 6 años. 35 del programa odontológico de 12 años y 28 del programa de la gestante. Se registró el COPD y ceod según corresponda, calculando el Índice de Significancia de Caries, Porcentaje Libre de Caries, Prevalencia de Caries, con Historia de Caries y el Índice de Cuidados.Resultados: Los índices COPD, ceod, ambas comunidades, mientras que el índice de cuidados es bajo.Conclusiones: Todos los índices son deficientes al compararlos con los observados a nivel regional, nacional e internacional. El índice de cuidados demuestra una baja eficiencia estimada del sistema de salud odontológico. Ambas comunidades están muy lejos de alcanzar las metas internacionales respecto a salud bucal. El porcentaje de población que no tiene acceso a tratamiento odontológico integral, es muy alto en ambas islas.Palabras clave: COPD, ceod, Índice de Significancia de Caries, Índice de Cuidados.abstRact Objective: To evaluate oral health indicators in the Municipality of Las Guaitecas and Huichas Islands, an area where oral health information is lacking.Materials and Method: A total of 104 dental files were considered; 63 from Guaitecas and 41 from Huichas Islands. Fourty-three were from the 6-year-program, 35 from the 12-year-dental program, and 28 from the pregnant women's program. DMFT and dmft (Decayed, Missing, Filled indices in teeth) were recorded as appropriate,
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