Diffuse sclerosing variant of Papillary Thyroid Carcinoma(DSPC) is an unusual type of Papillary Carcinoma that occurs in young patients. Clinically it can be mistaken for Hashimoto's Thyroiditis as it often presents as a diffuse firm thyroid swelling 3*. It is important to recognize this variant as the patients invariably have lymph node metastasis at the time of diagnosis.Contrary to the previous reports of a poor prognosis of this variant when compared to the classical papillary carcinoma, recent reports indicate a good prognosis(2,3). We report a case of DSPC occurring in a young boy.
Diagnosis of BE is hinged on the presence of intestinal metaplasia (IM) and inflammation in the lower esophagus. However IM can occur in the cardia and lower esophagus following reflux and helicobacter infection. The special stain for demonstrating intestinal metaplasia cannot distinguish IM in BE and that in cardia or lower esophagus due to other causes(1). Quite often biopsies labeled lower esophagus by the endoscopist may in fact be from the cardia especially in cases where the gastro-esophageal junction is indistinct.
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