Elderly people who attempt suicide have a high mortality both from completed suicide and death from other causes. The completed suicide rate is at least 1.5% per year, and the repetition rate is 5.4% per year. Those at risk of further self-harm are likely to be in contact with psychiatric services and to be suffering from persistent depression.
Depression and dementia in the elderly anti-depressants combinations are possibly hazardous. We present an open-trial of thyroxine augmentation in elderly patients diagnosed as suffering from resistant depression. Methods:Thyroxine 50 mcgld was added to F1uoxetine 20 mgld in patients who did not respond to previous. Non-SSRI. anti-depressant treatment. (6 weeks). nor to additional six weeks of Fluoxetine. Subjects: Subjects were diagnosed as suffering from major-depression. according to DSM-III-R criteria. All had normal thyroid function tests. ITSH and Ff 4). There were 15 patients in our series; 9 females. 6 males; mean age 72.1 years.
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