Our data suggest that pre-treatment FDG-PET/CT SUVmax cannot directly predict tumor response and survival, but it is strongly associated with tumor characteristics such as primary tumor stage and histology, being the first one of the most important and validated prognostic factors for anal cancer.

Concurrent CRT for elderly was feasible and quite well tolerated. Great attention in prescribing CT dose should be paid to limit acute toxicity.

Highlights Seroma was not associated with patient-reported breast appearance change after breast radiotherapy. Haematoma and smoking were significant risk factors for patient-reported breast appearance change. Seroma prevalence in our study was lower than previous reports.

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