A logistic regression model was created to control for potential known confounders. Results: There were 419 cases of ASBO with 253 (60.4%) females. The median age was 62 (15-93) years and the median ASA score was two (1-4). Index Operations consisted of Colorectal Surgery (n ¼ 159), Gynaecological Surgery (n ¼ 103), Appendicectomy (n ¼ 37) and miscellaneous procedures (n ¼ 120). Forty-nine (11.7%) patients required operative management of their ASBO and the median day-stay following ASBO was three (1-154) days. 151/419 (36%) patients were taking Statins at the time of admission-all for medical indications. Ten of these patients required surgery whilst the remaining 39 patients who required surgery were not taking Statins. Statin use was associated with a decreased need for surgery (p ¼ 0.02). The relative risk was 0.46 with an absolute risk reduction of 7.9% (95% CI: 2.1-13.7%). The number needed to treat was 13 (NNT ¼ 13; 95% CI: 7.3-46.8). Using a logistic regression model, age, gender, ASA score, presence of previous malignancy and sepsis were not significantly associated with need for surgery. GG was strongly associated with need for surgery (p ¼ 0.01). After controlling for all the factors mentioned above, Statin use remained associated with decreased need for surgery (p ¼ 0.04). The overall predictive model of need for surgery was significant (Chi-Squared value ¼ 23.3, p ¼ 0.01). Conclusion: Statin use is associated with decreased need for surgery in ASBO.
Validation of Quantitative Measurements of Obesity inColorectal Cancer Patients. C.
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