C. P. Sudheer scite author profile

Background: The term otomycosis is used to describe fungal infection of ear i.e. external auditory canal, eardrum. This condition appears as a primary infection or develops along with external bacterial infections as a results of antibiotic therapy. This study was designed to determine the clinical symptoms and fungal flora of otomycosis cases.Methods: A total 100 (53% males, 47% females) clinically diagnosed otomycosis cases between 06-70 years were included. The external auditory meatus debris was collected by sterile swabs and sent to the microbial laboratory investigations. Results: Highest prevalence was seen in the age group 21-30 years. Itching in the ear was commonest symptom in 89%, followed by ear ache. Positive fungal growth was seen in 94% cases. Aspergillus was the common isolate in 63% cases, followed by Aspergillus niger with Candida albicans (10%), penicillium in 4% cases and Candida in 3% cases. Coagulase negative Staphylococcus was seen in 32% cases, followed by Pseudomonas aeruginosa (12%), Staphylococcus aureus (16%), E. coli (11%).Conclusions: The genus most commonly involved in otomycosis is Aspergillus followed by Candida. Clinical improvement was seen in 91% of cases and most of the cases responded satisfactorily with topical clotrimazole.

Squamous cell carcinoma of maxillary sinus: a comparison of clinico-radiological staging with pre-operative staging

Sudheer

Singh²

2018

Background: The nasal cavity and paranasal sinuses are the site of origin of more complex, histologically diverse group of tumors which include neoplasms derived from mucosal epithelium, seromucinous glands and haematolymphoid cells. This study aimed to assess the incidence and prognosis of maxillary sinus malignancy.Methods: A total 25 (16 males, 09 females) malignancy cases between age group 11-70 years. All the cases were undergone with detailed clinical examination. The TNM staging system was followed to detect and standardize the disease stage. CT scan was used to identify the growth and extent of tumor. Results: Majority cases were between the age group 41-50 years (40%). Epistaxis was the commonest clinical symptom in 72% cases followed by nasal obstruction (68%), oral related symptoms (56%), oedema in cheeks (44%) and auditory disturbances in 16% cases. The TNM Staging system showed that 76% cases had T3 lesions, 16% had T4 lesions and 8% had T2 lesions. Nasal symptoms are commonly associated with malignancies and were belongs to T3 stage and few under T4.Conclusions: Maxillary sinus malignancy is an aggressive tumor normally diagnosed at the advanced stage, with minimal prognosis and reduced survival rate. Surgery in combination with radiotherapy followed by chemotherapy remains the best treatment modality.

Int J Med Sci Public Health

Assessment of relationship between tobacco consumption and laryngopharyngeal cancers

Sudheer¹,

T²

2017

Assessment of eustachian tube dysfunction in middle ear pathologies

Singh

Sudheer²

2018

Background: Auditory tube dysfunction is suspected as primary cause of chronic otitis media and leads to surgical related complications in otitis media with tympanic membrane perforation. The diagnosis of eustachian tube malfunction is essential to know the pathogenesis of chronic otitis media.Methods: A total 150 cases and 75 age, sex matched control subjects between age group 20-50 years were selected. Pre and post-surgical history was noted and detailed ear examination, tympanometry was done. Auditory tube function was evaluated through Valsalva test, nasopharyngoscopy, pneumatic otoscopy. Intact tympanic membrane was assessed by Williams test, perforated tympanic membrane by Toynbee’s test. Results: Postoperative assessment of eustachian tube function by Toynbee’s test for 19 cases with failed tympanoplasty showed normal ET function in 5 cases, 8 cases had partial and 6 cases had gross ET dysfunction. Postoperative assessment ET function by William’s test showed 4 cases among 19 cases had partial ET dysfunction and 01 cases had gross ET dysfunction.Conclusions: Efficient surgical outcome of middle ear complications always depends on eustachian tube function. Most of the cases with residual CP showed partial or gross ET dysfunction. Patients with tubal dysfunction should be evaluated for underlying cause and treatable causes should addressed before proceeding for surgery as it increases the success rate of tympanoplasty.

Assess the outcome of pre and postoperative bacterial culture in sinonasal polyposis cases under FESS

Sudheer¹,

Singh²

2019

Background: Sinonasal polyposis is multifactorial condition characterised by mucous membrane lesions in nose and paranasal sinuses. Pre and post-operative management of cases undergoing functional endoscopic sinus surgery (FESS) give ideal surgical outcome. This study designed to assess pre and postoperative bacterial profile in sinonasal polyposis cases undergoing Functional endoscopic sinus surgery.Methods: A total 100 cases ready for endonasal endoscopic surgery with chief complaints of sinonasal polyposis were recruited for the study. Pre and post-operative nasal swabs were collected from lateral wall, floor and area over the polyps. Sensitivity test was performed by using commonly available antibiotics i.e. ceftriaxone, erythromycin, ampicillin, gentamycin, ciprofloxacin, cephalexin, doxycycline and co-trimoxazole. Results: Pre-operative bacterial culture showed growth of Staphylococcus coagulase negative (CONS) in 32% cases, Staphylococcus aureus in 24%. Post-operative bacteria culture showed Staphylococcus coagulase negative (CONS) in 22% cases, Staphylococcus aureus in 22% cases. Staphylococcus coagulase negative (CONS) and Staphylococcus aureus had resistance to Ampicillin and Gentamycin.Conclusions: Staphylococcus coagulase negative (CONS) and Staphylococcus aureus are isolated commonly in pre and post-operative bacteria culture. Ampicillin, gentamicin, cefotaxime and ceftriaxone are primary choice for intravenous antibiotics in current clinical practice and in al surgical procedures including endoscopic sinus procedures.