Currently, composite materials have gained momentum in the field of orthopedics and maxillofacial surgery. Among the composite materials, ceramic/polymer possesses significant advantages of high mechanical reliability and excellent biocompatibility for applications in load bearing areas. In this work, polyethylene glycol (PEG)/hydroxyapatite (HAp) nanocomposites of varying weight percentages were synthesized and characterized physical-chemically by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), 31 P nuclear magnetic resonance (NMR), thermo gravimetric analysis (TGA), differential thermal analysis (DTA) and field emission-scanning electron microscopy (FE-SEM) and biologically by antimicrobial and anti-inflammatory assays to evaluate their potential use for biomedical applications. The results indicated that the size and crystallinity of HAp nanoparticles decrease with increase in PEG concentration in the composite. SEM confirmed the presence of HAp nanorod crystals in PEG matrix. The nano PEG-20/HAp demonstrated the highest antifungal and antibacterial activity and favorable inhibition of human cell hemolysis. The designed PEG/HAp nanocomposites constitute promising candidates for biomedical applications.
Among the composite materials, ceramic/ polymer possesses significant advantages of high mechanical reliability and excellent biocompatibility for applications in load-bearing areas. In this work, PVPCS(Poly (4-vinyl pyridine-co-styrene))/FHAp nanocomposites of varying weight percentages were synthesized and characterized physical-chemically by XRD, FTIR, 31 P NMR, TGA, DTA, and FE-SEM and biologically by antimicrobial and anti-inflammatory assays for evaluating their potential use for biomedical applications. The results indicated that the size and crystallinity of FHAp nanoparticles decrease with increase in PVPCS concentration in the composite. SEM confirmed the presence of FHAp nano rod crystals in PVPCS matrix. The nano PVPCS20/FHAp demonstrated the highest antifungal and antibacterial activity and favorable inhibition of human cell hemolysis. The designed PVPCS/FHAp nanocomposites constitute promising candidates for biomedical applications.
Abstract. Nano carbonated hydroxyapatite/Poly(4-vinyl pyridine-co-styrene) composites of varying composition for biomaterial applications have been synthesized. The nano carbonated hydroxyapatite/Poly(4-vinyl pyridine-co-styrene) composite materials were characterized by XRD, FTIR, 31 P NMR, TGA, DTA and FESEM. Carbonated Hydroxyapatite nano rod embedded composite was prepared using Poly(4-vinyl pyridine-co-styrene) as a matrix with different weight percentages (wt %). The results indicated that the size and crystallinity of Carbonated hydroxyapatite nano particles decreases with increase in Poly(4-vinyl pyridine-co-styrene) concentration in the composite. SEM confirms the presence of carbonated hydroxyapatite nano rod crystals in Poly(4-vinyl pyridine-co-styrene) matrix. Nano Carbonated hydroxyapatite/ Poly(4-vinyl pyridine-costyrene) composites were screened for antimicrobial activity and anti inflammatory activity.
A bstract-PV AlHAp nanocomposites of varying composition for biomaterial applications have been synthesized. The PV A/HAp nanocomposite materials were characterized by XRD, FTIR, 31p NMR, TGA, DTA and FESEM. Hydroxyapatite (HAp) nano rod embedded composite was prepared using poly (vinyl alcohol) (PV A) as a matrix with different weight percentages (wt %). The results indicated that the size and crystallinity of HAp nano particles decreases with increase in PV A concentration in the composite. SEM confirms the presence of HAp nano rod crystals in PV A matrix. PV AlHAp nano composites were screened for antimicrobial activity.
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