Objective. This study compared the eradication rates of of Helicobacter pylori (HP) infection by a 7-day and 14-day anti-HP regimen. Materials and Methods. An open, randomized, prospective study was performed to evaluate the response to anti-HP treatment in adult HP-positive patients following a 7-day course (Regimen A) of a proton pump inhibitor in association with clarithromycin and amoxicillin compared to a 14-day course (Regimen B). Gastric biopsies were performed at baseline and two months after anti-HP treatment. Results. Seventy-eight patients aged 18–64 years (28 males, 50 females) diagnosed with HP infection were included. Fifty-two (66.7%) patients received Regimen B and 26 (33.3%) Regimen A. The overall eradication rate was 70.5%. Better treatment response (p < 0.01) was seen in Regimen B (44/52, 84.2% versus 11/26, 42.3%). Significant improvement in histological features was seen in regimen B. There has been significant overall reduction in endoscopic aspects of gastric and duodenal lesions in both regimens. Younger patients ≤35 years had a better response to Regimen B. Better treatment response was seen in women, urban residents, and those with tertiary level of education in both groups. Conclusion. 14-day anti-HP regimen offered a significant better overall eradication of HP in study population.

Considering the highly nonlinear and non stationary features of the ECG signal proven by latest researches, the most appropriate methods of analysis are based also on the nonlinear dynamics; we used a modified root mean square analysis of a random walk, named detrended fluctuations analysis (DFA), which proved efficacy as diagnostic tool and advantages on the existing related methods.Our studies were conducted on two groups of young and old subjects, totally 24 patients, and the different behavior being related to the underlying dynamics of the heartbeat.We compare the data results using the DFA method: first when a line segment is fitted and second, when a quadratic polynomial is fitted in the least-squares sense Applications of this analysis may lead to new and safe diagnosis for patients and to evaluation of the patient status in systemic diseases that may affect in time the cardiovascular system.