allowed for the rapid, accurate location of selected structures. Some limitations remain. Correctly locating structures can be challenging for clustered, interlaced structures since interfering factors (obstructive/reflective structures, multi-story buildings, environmental diversity) may impact on the precision of GPS readings. Geospatial frames require constant updating, but could provide an approach for population-based investigations at probability samples of households in settings that are uncensused and lack longitudinal recording of socio-demographic and vital statistics.
Optimal control of low-density lipoprotein cholesterol (LDLc) is identified as a major target in reducing cardiovascular disease burden globally. However, existing lipid-lowering therapies have not been able to achieve LDLc targets even in developed countries. Therefore, novel therapies for the management of hyperlipidaemia are being trialled. Currently, there are three main groups of newer medicines; bempedoic acid, PCSK9 inhibitors and inclisiran, in addition to statins and ezetimibe in use for the management of hyperlipidaemia. This article aims to introduce these newer medicines and their clinical use in the treatment of hyperlipidaemia.
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