Temperature evolution and skin burn process resulting from a laser radiation exposure are investigated in this paper. Transient temperature in skin is numerically estimated using a 1-D multilayered model based on Penne's equation. The degree of burn injury is numerically evaluated by using an Arrhenius-type function. Unfortunately, most of the mathematical model parameters are not well defined in literature. Thus, a sensitivity analysis has been performed in order to evaluate the effect of each parameters inaccuracy on temperature estimation and on burn injuries prediction (according to several authors' characterization). Investigated parameters uncertainties that crucially invalidate the thermal model are as follows: epidermis and dermis volumetric heat, extinction coefficient, and skin thickness of the affected area. Considering the damage prediction, the activation energy is a key parameter for the validation of an efficient predictive tool.
Temperature evolution and skin burn process in biological samples exposed to laser radiation are investigated in this communication. A one-dimensional multi-layered model is presented and transient temperature is numerically estimated using a finite difference method. A damage function corresponding to the extent of burn injury and using the Arrhenius assumptions is proposed. Two experimental benches are presented in order to estimate human skin optical and thermal properties.
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